Reactome | daf-16 [nucleoplasm]

daf-16 [nucleoplasm]

Stable Identifier

R-CEL-199305

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

FOXO3, O16850

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O16850

Gene Names

daf-16

Reference Genes

BioGPS Gene:172981 daf-16

CTD Gene:172981 daf-16

ENSEMBL:WBGene00000912

Monarch:172981 daf-16

NCBI Gene:172981 daf-16

UCSC:O16850 daf-16

Wormbase:WBGene00000912

Reference Transcript

Other Identifiers

172981

175678_at

175823_s_at

181992_s_at

18457569

18458719

188176_s_at

A_12_P105570

A_12_P111652

A_12_P112051

A_12_P141320

A_12_P141321

CE28771

CE31056

CE_WBGene00000912_A

CGZ0032220

CGZ0032221

CGZ0032224

CGZ0032226

CGZ0032229

GO:0003674

GO:0003677

GO:0003700

GO:0006355

GO:0008150

GO:0009058

GO:0034641

GO:0043565

R13H8.1

R13H8.1a

R13H8.1b

R13H8.1c

R13H8.1d

R13H8.1f_1222-1281_0.901_14_C

R13H8.1f_827-886_0.906_13_A

R13H8.1f_945-1004_0.889_19_B

R13H8_1aP00173

R13H8_1aP00255

R13H8_1aP00482

R13H8_1bP00140

R13H8_1bP00444

R13H8_1bP01058

R13H8_1cP00139

R13H8_1dP00133

R13H8_1eP00055

R13H8_1eP00843

WBGene00000912

cea2.3.21962

cea2.c.05579

cea2.d.05039

cea2.d.35895

cea2.d.35914

cea2.d.35915

cea2.d.35932

Participates

as an input of

as an output of

SIRT1,SIRT3 deacetylate FOXO3 (Caenorhabditis elegans)

as a component of

Other forms of this molecule

phospho-daf-16 [nucleoplasm]

phospho-daf-16 [cytosol]

daf-16 [nucleoplasm]

daf-16 [cytosol]

daf-16 [nucleoplasm]

phospho-daf-16 [nucleoplasm]

phospho-daf-16 [cytosol]

Inferred From

FOXO3,(FOXO1,FOXO4) [nucleoplasm] (Homo sapiens)

FOXO3,(FOXO1) [nucleoplasm] (Homo sapiens)

FOXO3 [nucleoplasm] (Homo sapiens)

FOXO3,FOXO4 [nucleoplasm] (Homo sapiens)

FOXO3,FOXO4,(FOXO1) [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001251490.1, NP_001251492.1, NP_001021595.1, NP_001021597.1, NP_001021598.2, NP_001021596.1, NP_001021593.1, NP_001021594.1

PRO

O16850

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q2PJ68	6	phospho-sgk-1 [cytosol] (R-CEL-6795313-2) sgk-1 [cytosol] (R-CEL-2682364-2) phospho-sgk-1 [cytosol] (R-CEL-6795449-2) phospho-sgk-1 [nucleoplasm] (R-CEL-9612512-2) sgk-1 [cytosol] (R-CEL-2682351) sgk-1 [cytosol] (R-CEL-2682356-2)	0.676	3
UniProt:Q9XTG7	13	phospho-akt-2 [nucleoplasm] (R-CEL-198357-2) akt-2 [plasma membrane] (R-CEL-2976006-2) phospho-akt-2 [plasma membrane] (R-CEL-3009363-2) phospho-akt-2 [cytosol] (R-CEL-198634-2) phospho-akt-2 [cytosol] (R-CEL-3009370-2) akt-2 [cytosol] (R-CEL-58252-2) phospho-akt-2 [plasma membrane] (R-CEL-199430-2) phospho-akt-2 [cytosol] (R-CEL-198356-2) akt-2 [cytosol] (R-CEL-2976007-2) phospho-akt-2 [cytosol] (R-CEL-3009367-2) phospho-akt-2 [plasma membrane] (R-CEL-377265-2) phospho-akt-2 [nucleoplasm] (R-CEL-3009365-2) akt-2 [plasma membrane] (R-CEL-199416-2)	0.676	3
UniProt:Q17941	19	phospho-akt-1 [nucleoplasm] (R-CEL-198357) phospho-akt-1 [nucleoplasm] (R-CEL-202087) akt-1 [plasma membrane] (R-CEL-2976006) phospho-akt-1 [plasma membrane] (R-CEL-3009363) akt-1 [cytosol] (R-CEL-49859) phospho-akt-1 [cytosol] (R-CEL-3009370) akt-1 [cytosol] (R-CEL-58252) phospho-akt-1 [plasma membrane] (R-CEL-2317312) phospho-akt-1 [cytosol] (R-CEL-166800) phospho-akt-1 [plasma membrane] (R-CEL-199430) phospho-akt-1 [cytosol] (R-CEL-202066) phospho-akt-1 [cytosol] (R-CEL-198634) phospho-akt-1 [cytosol] (R-CEL-198356) akt-1 [plasma membrane] (R-CEL-202053) phospho-akt-1 [plasma membrane] (R-CEL-377265) akt-1 [cytosol] (R-CEL-2976007) phospho-akt-1 [cytosol] (R-CEL-3009367) akt-1 [plasma membrane] (R-CEL-199416) phospho-akt-1 [nucleoplasm] (R-CEL-3009365)	0.676	3
UniProt:Q21921	1	sir-2.1 [nucleoplasm] (R-CEL-427531)	0.589	2
IntAct:EBI-16221250 HCF1			0.524	2
UniProt:Q9N5V3 Q9N5V3			0.488	2

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