Reactome | SGK1 [cytosol]

SGK1 [cytosol]

Stable Identifier

R-CEL-2682356

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

Q2PJ68

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional Regulation by TP53 (Caenorhabditis elegans)
      - Regulation of TP53 Activity (Caenorhabditis elegans)
        
        Regulation of TP53 Expression and Degradation (Caenorhabditis elegans)
        
        Regulation of TP53 Degradation (Caenorhabditis elegans)
        
        mTORC2 phosphorylates SGK1 (Caenorhabditis elegans)
        
        SGK1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q2PJ68

Reference Genes

BioGPS Gene:181697

CTD Gene:181697

ENSEMBL:WBGene00004789

KEGG:cel:CELE_W10G6.2

Monarch:181697

NCBI Gene:181697

UCSC:Q2PJ68

Wormbase:WBGene00004789

Reference Transcript

Other Identifiers

181697

GO:0000166

GO:0002119

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005547

GO:0005634

GO:0005737

GO:0005886

GO:0006468

GO:0006629

GO:0010468

GO:0016020

GO:0016301

GO:0016324

GO:0016740

GO:0035556

GO:0046872

GO:0048382

GO:0048856

GO:0106310

GO:0140096

GO:1902911

GO:1903188

GO:1904508

Participates

as a member of

SGK1/2/3 [cytosol] (Caenorhabditis elegans)

as an input of

mTORC2 phosphorylates SGK1 (Caenorhabditis elegans)

Other forms of this molecule

SGK3 [cytosol]

SGK2 [cytosol]

phospho-p-S422-SGK1 [cytosol]

phospho-p-T256,S422-SGK1 [cytosol]

phospho-p-T256,S422-SGK1 [nucleoplasm]

Inferred From

SGK1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001041299.1, NP_001367134.1

ENSEMBL

W10G6.2b.1, W10G6.2b.1, WBGene00004789

PRO

Q2PJ68

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O16850	19	daf-16 [nucleoplasm] (R-CEL-5690183) daf-16 [nucleoplasm] (R-CEL-199300) daf-16 [nucleoplasm] (R-CEL-199305) daf-16 [nucleoplasm] (R-CEL-9614396) phospho-daf-16 [nucleoplasm] (R-CEL-9614995) phospho-daf-16 [nucleoplasm] (R-CEL-199314) phospho-daf-16 [nucleoplasm] (R-CEL-199306) phospho-daf-16 [nucleoplasm] (R-CEL-199289) phospho-daf-16 [cytosol] (R-CEL-9614413) phospho-daf-16 [cytosol] (R-CEL-211158) phospho-daf-16 [cytosol] (R-CEL-9614415) daf-16 [nucleoplasm] (R-CEL-9620514) daf-16 [mitochondrial matrix] (R-CEL-9841849) daf-16 [mitochondrial matrix] (R-CEL-9841824) daf-16 [cytosol] (R-CEL-5687032) daf-16 [nucleoplasm] (R-CEL-6782501) phospho-daf-16 [cytosol] (R-CEL-5687014) phospho-daf-16 [nucleoplasm] (R-CEL-5687010) phospho-daf-16 [nucleoplasm] (R-CEL-5692651)	0.676	3
UniProt:Q9XTG7	15	phospho-p-S473-AKT1 [cytosol] (R-CEL-9841264-2) phospho-p-T308,S473-AKT1 [plasma membrane] (R-CEL-199430-2) phospho-p-Y315,Y326-AKT1 [cytosol] (R-CEL-8848757-2) phospho-p-T308-AKT1 [cytosol] (R-CEL-198634-2) phospho-p-T305-AKT3 [cytosol] (R-CEL-3009370-2) AKT1 [cytosol] (R-CEL-58252-2) AKT3 [cytosol] (R-CEL-2976007-2) AKT1 [plasma membrane] (R-CEL-199416-2) AKT3 [plasma membrane] (R-CEL-2976006-2) phospho-p-S473-AKT1 [plasma membrane] (R-CEL-377265-2) phospho-p-S472-AKT3 [plasma membrane] (R-CEL-3009363-2) phospho-p-T308,S473-AKT1 [cytosol] (R-CEL-198356-2) phospho-p-T305,S472-AKT3 [cytosol] (R-CEL-3009367-2) phospho-p-T308,S473-AKT1 [nucleoplasm] (R-CEL-198357-2) phospho-p-T305,S472-AKT3 [nucleoplasm] (R-CEL-3009365-2)	0.567	3
UniProt:Q17941	20	phospho-p-T309,S474-AKT2 [nucleoplasm] (R-CEL-202087) phospho-p-T305,S472-AKT3 [nucleoplasm] (R-CEL-3009365) phospho-p-T308,S473-AKT1 [nucleoplasm] (R-CEL-198357) phospho-p-T305,S472-AKT3 [cytosol] (R-CEL-3009367) phospho-p-T309,S474-AKT2 [cytosol] (R-CEL-202062) phospho-p-T308,S473-AKT1 [cytosol] (R-CEL-198356) phospho-p-S474-AKT2 [plasma membrane] (R-CEL-2317312) phospho-p-S472-AKT3 [plasma membrane] (R-CEL-3009363) phospho-p-S473-AKT1 [plasma membrane] (R-CEL-377265) AKT2 [plasma membrane] (R-CEL-202053) AKT3 [plasma membrane] (R-CEL-2976006) AKT1 [plasma membrane] (R-CEL-199416) AKT2 [cytosol] (R-CEL-49859) AKT3 [cytosol] (R-CEL-2976007) AKT1 [cytosol] (R-CEL-58252) phospho-p-T309-AKT2 [cytosol] (R-CEL-202066) phospho-p-T305-AKT3 [cytosol] (R-CEL-3009370) phospho-p-T308-AKT1 [cytosol] (R-CEL-198634) phospho-p-Y315,Y326-AKT1 [cytosol] (R-CEL-8848757) phospho-p-T308,S473-AKT1 [plasma membrane] (R-CEL-199430)	0.567	3

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