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phospho-p-S474-AKT2 [plasma membrane]
Stable Identifier
R-CEL-2317312
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
plasma membrane
Synonyms
Q17941
Locations in the PathwayBrowser
Expand all
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Regulation of T cell activation by CD28 family (Caenorhabditis elegans)
Co-stimulation by CD28 (Caenorhabditis elegans)
CD28 dependent PI3K/Akt signaling (Caenorhabditis elegans)
AKT binds PDPK1 (Caenorhabditis elegans)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
mTORC2 phosphorylates AKT at S473 (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
AKT binds PDPK1 (Caenorhabditis elegans)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
mTORC2 phosphorylates AKT at S473 (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
AKT binds PDPK1 (Caenorhabditis elegans)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
mTORC2 phosphorylates AKT at S473 (Caenorhabditis elegans)
p-S-AKT:PIP3 [plasma membrane] (Caenorhabditis elegans)
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
phospho-p-S474-AKT2 [plasma membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q17941
Reference Genes
BioGPS Gene:179424
CTD Gene:179424
ENSEMBL:WBGene00000102
KEGG:cel:CELE_C12D8.10
Monarch:179424
NCBI Gene:179424
UCSC:Q17941
Wormbase:WBGene00000102
Wormbase:WBGene00000102
Reference Transcript
RefSeq:NM_001028476.7
RefSeq:NM_001028474.8
RefSeq:NM_001028475.5
Other Identifiers
179424
GO:0000166
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005516
GO:0005524
GO:0005547
GO:0006468
GO:0006935
GO:0007635
GO:0008286
GO:0008289
GO:0008340
GO:0008582
GO:0009898
GO:0010468
GO:0016301
GO:0016740
GO:0030424
GO:0030425
GO:0035556
GO:0042771
GO:0043025
GO:0043066
GO:0043536
GO:0045087
GO:0046872
GO:0098542
GO:0106310
GO:0140096
GO:1902074
GO:1902911
Participates
as a candidate of
p-S-AKT [plasma membrane] (Caenorhabditis elegans)
Other forms of this molecule
phospho-p-T309,S474-AKT2 [nucleoplasm]
phospho-p-T305,S472-AKT3 [nucleoplasm]
phospho-p-T308,S473-AKT1 [nucleoplasm]
phospho-p-T305,S472-AKT3 [cytosol]
phospho-p-T309,S474-AKT2 [cytosol]
phospho-p-T308,S473-AKT1 [cytosol]
phospho-p-S472-AKT3 [plasma membrane]
phospho-p-S473-AKT1 [plasma membrane]
AKT2 [plasma membrane]
AKT3 [plasma membrane]
AKT1 [plasma membrane]
AKT2 [cytosol]
AKT3 [cytosol]
AKT1 [cytosol]
phospho-p-T309-AKT2 [cytosol]
phospho-p-T305-AKT3 [cytosol]
phospho-p-T308-AKT1 [cytosol]
phospho-p-Y315,Y326-AKT1 [cytosol]
phospho-p-T308,S473-AKT1 [plasma membrane]
phospho-p-S473-AKT1 [cytosol]
Inferred From
p-S474-AKT2 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 474 (in Homo sapiens)
Coordinate
474
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001023647.1
,
NP_001023646.1
,
NP_001023645.1
ENSEMBL
WBGene00000102
,
C12D8.10a.1
,
C12D8.10a.1
PRO
Q17941
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O16850
19
daf-16 [nucleoplasm]
(R-CEL-5690183)
daf-16 [nucleoplasm]
(R-CEL-199300)
daf-16 [nucleoplasm]
(R-CEL-199305)
daf-16 [nucleoplasm]
(R-CEL-9614396)
phospho-daf-16 [nucleoplasm]
(R-CEL-9614995)
phospho-daf-16 [nucleoplasm]
(R-CEL-199314)
phospho-daf-16 [nucleoplasm]
(R-CEL-199306)
phospho-daf-16 [nucleoplasm]
(R-CEL-199289)
phospho-daf-16 [cytosol]
(R-CEL-9614413)
phospho-daf-16 [cytosol]
(R-CEL-211158)
phospho-daf-16 [cytosol]
(R-CEL-9614415)
daf-16 [nucleoplasm]
(R-CEL-9620514)
daf-16 [mitochondrial matrix]
(R-CEL-9841849)
daf-16 [mitochondrial matrix]
(R-CEL-9841824)
daf-16 [cytosol]
(R-CEL-5687032)
daf-16 [nucleoplasm]
(R-CEL-6782501)
phospho-daf-16 [cytosol]
(R-CEL-5687014)
phospho-daf-16 [nucleoplasm]
(R-CEL-5687010)
phospho-daf-16 [nucleoplasm]
(R-CEL-5692651)
0.676
3
UniProt:Q2PJ68
6
SGK3 [cytosol]
(R-CEL-2682351)
SGK2 [cytosol]
(R-CEL-2682364)
SGK1 [cytosol]
(R-CEL-2682356)
phospho-p-S422-SGK1 [cytosol]
(R-CEL-6795313)
phospho-p-T256,S422-SGK1 [cytosol]
(R-CEL-6795449)
phospho-p-T256,S422-SGK1 [nucleoplasm]
(R-CEL-9612512)
0.567
3
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