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phospho-p-S422-SGK1 [cytosol]
Stable Identifier
R-CEL-6795313
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
Q2PJ68
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
Regulation of TP53 Activity (Caenorhabditis elegans)
Regulation of TP53 Expression and Degradation (Caenorhabditis elegans)
Regulation of TP53 Degradation (Caenorhabditis elegans)
PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
phospho-p-S422-SGK1 [cytosol] (Caenorhabditis elegans)
mTORC2 phosphorylates SGK1 (Caenorhabditis elegans)
phospho-p-S422-SGK1 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
phospho-p-S422-SGK1 [cytosol] (Caenorhabditis elegans)
mTORC2 phosphorylates SGK1 (Caenorhabditis elegans)
phospho-p-S422-SGK1 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q2PJ68
Reference Genes
BioGPS Gene:181697
CTD Gene:181697
ENSEMBL:WBGene00004789
KEGG:cel:CELE_W10G6.2
Monarch:181697
NCBI Gene:181697
UCSC:Q2PJ68
Wormbase:WBGene00004789
Wormbase:WBGene00004789
Reference Transcript
RefSeq:NM_001047834.4
RefSeq:NM_001381177.2
Other Identifiers
181697
GO:0000166
GO:0002119
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005547
GO:0005634
GO:0005737
GO:0005886
GO:0006468
GO:0006629
GO:0010468
GO:0016020
GO:0016301
GO:0016324
GO:0016740
GO:0035556
GO:0046872
GO:0048382
GO:0048856
GO:0106310
GO:0140096
GO:1902911
GO:1903188
GO:1904508
Participates
as an input of
PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
as an output of
mTORC2 phosphorylates SGK1 (Caenorhabditis elegans)
Other forms of this molecule
SGK3 [cytosol]
SGK2 [cytosol]
SGK1 [cytosol]
phospho-p-T256,S422-SGK1 [cytosol]
phospho-p-T256,S422-SGK1 [nucleoplasm]
Inferred From
p-S422-SGK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 422 (in Homo sapiens)
Coordinate
422
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001041299.1
,
NP_001367134.1
ENSEMBL
W10G6.2b.1
,
W10G6.2b.1
,
WBGene00004789
PRO
Q2PJ68
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O16850
19
daf-16 [nucleoplasm]
(R-CEL-5690183)
daf-16 [nucleoplasm]
(R-CEL-199300)
daf-16 [nucleoplasm]
(R-CEL-199305)
daf-16 [nucleoplasm]
(R-CEL-9614396)
phospho-daf-16 [nucleoplasm]
(R-CEL-9614995)
phospho-daf-16 [nucleoplasm]
(R-CEL-199314)
phospho-daf-16 [nucleoplasm]
(R-CEL-199306)
phospho-daf-16 [nucleoplasm]
(R-CEL-199289)
phospho-daf-16 [cytosol]
(R-CEL-9614413)
phospho-daf-16 [cytosol]
(R-CEL-211158)
phospho-daf-16 [cytosol]
(R-CEL-9614415)
daf-16 [nucleoplasm]
(R-CEL-9620514)
daf-16 [mitochondrial matrix]
(R-CEL-9841849)
daf-16 [mitochondrial matrix]
(R-CEL-9841824)
daf-16 [cytosol]
(R-CEL-5687032)
daf-16 [nucleoplasm]
(R-CEL-6782501)
phospho-daf-16 [cytosol]
(R-CEL-5687014)
phospho-daf-16 [nucleoplasm]
(R-CEL-5687010)
phospho-daf-16 [nucleoplasm]
(R-CEL-5692651)
0.676
3
UniProt:Q9XTG7
15
phospho-p-S473-AKT1 [cytosol]
(R-CEL-9841264-2)
phospho-p-T308,S473-AKT1 [plasma membrane]
(R-CEL-199430-2)
phospho-p-Y315,Y326-AKT1 [cytosol]
(R-CEL-8848757-2)
phospho-p-T308-AKT1 [cytosol]
(R-CEL-198634-2)
phospho-p-T305-AKT3 [cytosol]
(R-CEL-3009370-2)
AKT1 [cytosol]
(R-CEL-58252-2)
AKT3 [cytosol]
(R-CEL-2976007-2)
AKT1 [plasma membrane]
(R-CEL-199416-2)
AKT3 [plasma membrane]
(R-CEL-2976006-2)
phospho-p-S473-AKT1 [plasma membrane]
(R-CEL-377265-2)
phospho-p-S472-AKT3 [plasma membrane]
(R-CEL-3009363-2)
phospho-p-T308,S473-AKT1 [cytosol]
(R-CEL-198356-2)
phospho-p-T305,S472-AKT3 [cytosol]
(R-CEL-3009367-2)
phospho-p-T308,S473-AKT1 [nucleoplasm]
(R-CEL-198357-2)
phospho-p-T305,S472-AKT3 [nucleoplasm]
(R-CEL-3009365-2)
0.567
3
UniProt:Q17941
20
phospho-p-T309,S474-AKT2 [nucleoplasm]
(R-CEL-202087)
phospho-p-T305,S472-AKT3 [nucleoplasm]
(R-CEL-3009365)
phospho-p-T308,S473-AKT1 [nucleoplasm]
(R-CEL-198357)
phospho-p-T305,S472-AKT3 [cytosol]
(R-CEL-3009367)
phospho-p-T309,S474-AKT2 [cytosol]
(R-CEL-202062)
phospho-p-T308,S473-AKT1 [cytosol]
(R-CEL-198356)
phospho-p-S474-AKT2 [plasma membrane]
(R-CEL-2317312)
phospho-p-S472-AKT3 [plasma membrane]
(R-CEL-3009363)
phospho-p-S473-AKT1 [plasma membrane]
(R-CEL-377265)
AKT2 [plasma membrane]
(R-CEL-202053)
AKT3 [plasma membrane]
(R-CEL-2976006)
AKT1 [plasma membrane]
(R-CEL-199416)
AKT2 [cytosol]
(R-CEL-49859)
AKT3 [cytosol]
(R-CEL-2976007)
AKT1 [cytosol]
(R-CEL-58252)
phospho-p-T309-AKT2 [cytosol]
(R-CEL-202066)
phospho-p-T305-AKT3 [cytosol]
(R-CEL-3009370)
phospho-p-T308-AKT1 [cytosol]
(R-CEL-198634)
phospho-p-Y315,Y326-AKT1 [cytosol]
(R-CEL-8848757)
phospho-p-T308,S473-AKT1 [plasma membrane]
(R-CEL-199430)
0.567
3
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