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Tyrosine kinase inhibitors of FGFR2 mutants [cytosol]
Stable Identifier
R-ALL-2077403
Type
Set [DefinedSet]
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR2 in disease (Homo sapiens)
FGFR2 mutant receptor activation (Homo sapiens)
Activated point mutants of FGFR2 (Homo sapiens)
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)
Tyrosine kinase inhibitors of FGFR2 mutants [cytosol]
FGFR2 point mutant dimers:TKIs [plasma membrane] (Homo sapiens)
Tyrosine kinase inhibitors of FGFR2 mutants [cytosol]
Participants
members
AZD4547 [cytosol]
lenvatinib [cytosol]
PD173074 [cytosol]
E3810 [cytosol]
SU5402 [cytosol]
BGJ398 [cytosol]
pazopanib [cytosol]
Participates
as a component of
FGFR2 point mutant dimers:TKIs [plasma membrane] (Homo sapiens)
as an input of
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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