lenvatinib [cytosol]

Stable Identifier
R-ALL-2023393
Type
ChemicalDrug
Compartment
cytosol
Synonyms
E7080
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General
E7080 is a broad-specificity tyrosine kinase inhibitor that is in Phase I clinical trials for a variety of solid malignancies, including metastatic endometrial cancer (NCT01111461). No specific data regarding its preclinical efficacy against activated FGF receptors is available.
Literature References
PubMed ID Title Journal Year
17943726 E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

Asada, M, Yamamoto, Y, Matsui, J, Tsuruoka, A, Uenaka, T, Funahashi, Y, Wakabayashi, T, Watanabe, T

Int J Cancer 2008
External Reference Information
External Reference
lenvatinib [Guide to Pharmacology:7426]
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as a member of
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
ChEBI
Pharos - Ligands
PharmacoDB
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