E3810 [cytosol]

Stable Identifier
R-ALL-2023389
Type
ChemicalDrug
Compartment
Synonyms
lucitanib, E-3810
Locations in the PathwayBrowser
General

E-3810 is a dual VEGFR and FGFR inhibitor that has anti-angiogenic and anti-tumorigenic effects in preclinical studies (Bello, 2011). It is in Phase I clinical trials for patients with solid tumors (NCT01283945).

Literature References
PubMed ID Title Journal Year
21212416 E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models

Bello, E, Colella, G, Scarlato, V, Oliva, P, Berndt, A, Valbusa, G, Serra, SC, D'Incalci, M, Cavalletti, E, Giavazzi, R, Damia, G, Camboni, G

Cancer Res 2011
External Reference Information
External Reference
Participates
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
ChEBI
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