Reactome | LIG1 [nucleoplasm]

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LIG1 [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:10447902] DNA ligase activity of LIG1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-SSC-5651810] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] - Sus scrofa [Complex:R-SSC-5651769] LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-110371] LIG1 binds APEX1 and PCNA at SSB - Sus scrofa [Reaction:R-SSC-5651773] LIG1 binds POLB at long-patch BER site - Sus scrofa [BlackBoxEvent:R-SSC-9980021] LIG1 binds SSA sites - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10447901
displayName	LIG1 [nucleoplasm]
endCoordinate	919
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-53787] LIG1 [nucleoplasm] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-SSC-5690475] LIG1,LIG3:XRCC1 [nucleoplasm] - Sus scrofa
name	LIG1 LIG1 A0A5G2R0M7
producedByEvent	[BlackBoxEvent:R-SSC-5686663] Completion of SSA - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A5G2R0M7] UniProt:A0A5G2R0M7
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-53787
startCoordinate	1

Referrals

(activeUnit)	[CatalystActivity:10516807] DNA ligase activity of LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] [CatalystActivity:10516802] DNA ligase activity of LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] [CatalystActivity:10520324] DNA ligase activity of LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm]
(hasComponent)	[Complex:R-SSC-5651810] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] [Complex:R-SSC-5651808] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] [Complex:R-SSC-5651769] LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] [Complex:R-SSC-5651790] LIG1:POLB:dsDNA [nucleoplasm] [Complex:R-SSC-9980008] LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm]
(input)	[Reaction:R-SSC-110371] LIG1 binds APEX1 and PCNA at SSB [Reaction:R-SSC-5651773] LIG1 binds POLB at long-patch BER site [BlackBoxEvent:R-SSC-9980021] LIG1 binds SSA sites
(hasMember)	[DefinedSet:R-SSC-5690475] LIG1,LIG3:XRCC1 [nucleoplasm]
(output)	[BlackBoxEvent:R-SSC-5686663] Completion of SSA
(physicalEntity)	[CatalystActivity:10447902] DNA ligase activity of LIG1 [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-53787] LIG1 [nucleoplasm]