Reactome | Completion of SSA

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Completion of SSA Show undefined attributes

catalystActivity	[CatalystActivity:10520324] DNA ligase activity of LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10520326
displayName	Completion of SSA
eventOf	[Pathway:R-SSC-5685938] HDR through Single Strand Annealing (SSA) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-5686663] Completion of SSA - Homo sapiens
input	[Complex:R-SSC-9980008] LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Completion of SSA
output	[Complex:R-SSC-176269] ATR:ATRIP [nucleoplasm] [OtherEntity:R-ALL-5686649] dsDNA with inter-SSA deletion [nucleoplasm] [Complex:R-SSC-109943] ERCC1:ERCC4 [nucleoplasm] [DefinedSet:R-SSC-5685980] EXO1,DNA2:BLM,WRN [nucleoplasm] 2 × [OtherEntity:R-ALL-68454] Flap [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-3321979] KAT5 [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-53787] LIG1 [nucleoplasm] [DefinedSet:R-SSC-9707299] p-5S-BRCA1:p-2T-BARD1 [nucleoplasm] [Complex:R-SSC-5682166] p-MRN [nucleoplasm] [Complex:R-SSC-5685169] p-RPA heterotrimer [nucleoplasm] [Complex:R-SSC-5684137] p-S327,T847,T859-RBBP8 homotetramer [nucleoplasm] [Complex:R-SSC-5686589] p-Y104-RAD52 heptamer [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5693527] phospho-ATM [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5687710] phospho-BRIP1 [nucleoplasm] [Complex:R-SSC-176353] RAD17:RFC [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-62637] RAD51 [nucleoplasm] [Complex:R-SSC-176312] RAD9:HUS1:RAD1 [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5684880] RHNO1 [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5684878] TOPBP1 [nucleoplasm]
precedingEvent	[Reaction:R-SSC-5686657] ERCC1:XPF cleaves flaps generated by SSA - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-5686663
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-5685938] HDR through Single Strand Annealing (SSA)
(inferredTo)	[BlackBoxEvent:R-HSA-5686663] Completion of SSA

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