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LIG1 [nucleoplasm]
Stable Identifier
R-SSC-53787
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
LIG1, A0A5G2R0M7
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
S Phase (Sus scrofa)
Synthesis of DNA (Sus scrofa)
DNA strand elongation (Sus scrofa)
Lagging Strand Synthesis (Sus scrofa)
Processive synthesis on the lagging strand (Sus scrofa)
Joining of adjacent Okazaki fragments (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
Chromosome Maintenance (Sus scrofa)
Telomere Maintenance (Sus scrofa)
Extension of Telomeres (Sus scrofa)
Telomere C-strand (Lagging Strand) Synthesis (Sus scrofa)
Processive synthesis on the C-strand of the telomere (Sus scrofa)
Joining of adjacent Okazaki fragments of the C-strand (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
Base Excision Repair (Sus scrofa)
Resolution of Abasic Sites (AP sites) (Sus scrofa)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Sus scrofa)
PCNA-Dependent Long Patch Base Excision Repair (Sus scrofa)
LIG1 binds APEX1 and PCNA at SSB (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1 bound to APEX1 and PCNA ligates SSB (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
POLB-Dependent Long Patch Base Excision Repair (Sus scrofa)
LIG1 binds POLB at long-patch BER site (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1 bound to POLB ligates SSB (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:POLB:dsDNA [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
Homology Directed Repair (Sus scrofa)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
HDR through Single Strand Annealing (SSA) (Sus scrofa)
Completion of SSA (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1 binds SSA sites (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
Mismatch Repair (Sus scrofa)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Sus scrofa)
DNA ligase I ligates single stranded nick in double stranded DNA (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Sus scrofa)
DNA ligase I ligates single stranded nick in double stranded DNA (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
Nucleotide Excision Repair (Sus scrofa)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Sus scrofa)
Gap-filling DNA repair synthesis and ligation in TC-NER (Sus scrofa)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Sus scrofa)
LIG1,LIG3:XRCC1 [nucleoplasm] (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
DNA Replication (Sus scrofa)
Synthesis of DNA (Sus scrofa)
DNA strand elongation (Sus scrofa)
Lagging Strand Synthesis (Sus scrofa)
Processive synthesis on the lagging strand (Sus scrofa)
Joining of adjacent Okazaki fragments (Sus scrofa)
LIG1 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2R0M7
Gene Names
LIG1
Reference Genes
ENSEMBL:ENSSSCG00000003128.5
UCSC:A0A5G2R0M7 LIG1
Other Identifiers
100520434
GO:0000166
GO:0003677
GO:0003824
GO:0003909
GO:0003910
GO:0005524
GO:0005634
GO:0005654
GO:0006260
GO:0006273
GO:0006281
GO:0006284
GO:0006310
GO:0006974
GO:0016874
GO:0051301
GO:0071897
GO:0140097
GO:1903461
Ssc.24549.1.S1_at
Participates
as a component of
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Sus scrofa)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Sus scrofa)
LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Sus scrofa)
LIG1:POLB:dsDNA [nucleoplasm] (Sus scrofa)
LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
as an input of
LIG1 binds APEX1 and PCNA at SSB (Sus scrofa)
LIG1 binds POLB at long-patch BER site (Sus scrofa)
LIG1 binds SSA sites (Sus scrofa)
as a member of
LIG1,LIG3:XRCC1 [nucleoplasm] (Sus scrofa)
as an output of
Completion of SSA (Sus scrofa)
Inferred From
LIG1 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSSSCG00000003128
,
ENSSSCP00000070663
,
ENSSSCT00000068819
VGNC
89720
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