Reactome | FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-3465459] FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling - Rattus norvegicus [Reaction:R-RNO-73945] FAS-mediated dimerization of procaspase-8 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10107925
displayName	FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-57031] Casp8 [cytosol] [Complex:R-RNO-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-75114] FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] - Homo sapiens
maxDepth	5
name	FASL:FAS trimer:FADD:CASP8(1-479)
producedByEvent	[Reaction:R-RNO-83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-75114
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-3465459] FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling [Reaction:R-RNO-73945] FAS-mediated dimerization of procaspase-8
(output)	[Reaction:R-RNO-83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8
(inferredTo)	[Complex:R-HSA-75114] FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane]

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