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What is Reactome ?
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Table of Contents
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Traf2 [cytosol]
Stable Identifier
R-RNO-66370
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
TRAF2, B5DFH7
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFR2 non-canonical NF-kB pathway (Rattus norvegicus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Rattus norvegicus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] (Rattus norvegicus)
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Protesomal degradation of K48polyUb-TRAF3 (Rattus norvegicus)
TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] (Rattus norvegicus)
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Rattus norvegicus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Rattus norvegicus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Rattus norvegicus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:cIAP1/2 complex binds FN14:TWEAK (Rattus norvegicus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF3 binds BAFFR:BAFF (Rattus norvegicus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAFs bind RANK:RANKL (Rattus norvegicus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Rattus norvegicus)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Rattus norvegicus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF3:NIK binds TRAF2:cIAP1/2 (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Rattus norvegicus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Rattus norvegicus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Deubiquitination (Rattus norvegicus)
Ub-specific processing proteases (Rattus norvegicus)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Rattus norvegicus)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
USP4 deubiquitinate TRAF2,TRAF6 (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Caspase activation via extrinsic apoptotic signalling pathway (Rattus norvegicus)
Caspase activation via Death Receptors in the presence of ligand (Rattus norvegicus)
Dimerization of procaspase-8 (Rattus norvegicus)
TNF-mediated dimerization of procaspase-8 (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIP1:FADD:2xCASP8(1-479) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Regulation by c-FLIP (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at DISC (Rattus norvegicus)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
Regulation of necroptotic cell death (Rattus norvegicus)
CASP8 activity is inhibited (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
FLIP(S) and procaspase-8 form heterodimer (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8 (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
Regulation of TNFR1 signaling (Rattus norvegicus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at TNFR signaling complex (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
K63polyUb-RIPK1 is deubiquitinated (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
LUBAC ubiquitinates RIPK1 at K627 (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
OPTN binds polyUb-RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
OPTN recruits CYLD to the TNFR1 complex (Rattus norvegicus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8 (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8:FLIP(L) (Rattus norvegicus)
TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L) [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Rattus norvegicus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Rattus norvegicus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
ULK1 phosphorylates RIPK1 at S357 (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:p-S357-RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFR1-induced NF-kappa-B signaling pathway (Rattus norvegicus)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNFR1-induced proapoptotic signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1 complex binds FADD (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:p-S357-RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex. (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Traf2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:B5DFH7
Gene Names
Traf2
Reference Genes
BioGPS Gene:311786 Traf2
ENSEMBL:ENSRNOG00000006238
ENSEMBL:ENSRNOG00000006238.7 Traf2
KEGG Gene (Rattus norvegicus):311786 Traf2
Monarch:311786 Traf2
NCBI Gene:311786 Traf2
UCSC:B5DFH7 Traf2
Reference Transcript
RefSeq:XM_008761588.2 Traf2
RefSeq:XM_006233594.3 Traf2
RefSeq:NM_001107815.2 Traf2
Other Identifiers
10843483
1372664_at
17770315
311786
5736898
5773142
5857827
5939701
6091635
6098699
6165175
6314258
6435143
6593344
6723740
A_44_P241277
GE1168699
GO:0000151
GO:0002376
GO:0002637
GO:0002726
GO:0002947
GO:0003824
GO:0004842
GO:0005164
GO:0005174
GO:0005515
GO:0005737
GO:0005783
GO:0005829
GO:0005886
GO:0007165
GO:0007250
GO:0008270
GO:0008289
GO:0009898
GO:0012501
GO:0012506
GO:0016071
GO:0016740
GO:0019899
GO:0019901
GO:0019903
GO:0023019
GO:0023052
GO:0030163
GO:0030674
GO:0031625
GO:0031996
GO:0032743
GO:0033209
GO:0035591
GO:0035631
GO:0036211
GO:0038061
GO:0042802
GO:0042981
GO:0043120
GO:0043123
GO:0043226
GO:0043254
GO:0044877
GO:0045087
GO:0045121
GO:0046328
GO:0046625
GO:0046872
GO:0048255
GO:0051865
GO:0060090
GO:0065003
GO:0070534
GO:0071732
GO:0097057
GO:0097300
GO:0097400
GO:0098542
GO:0140096
GO:1903265
GO:1990604
GO:2001238
ILMN_1373728
PH_rn_0011059
rc_AI058577_i_at
rc_AI058577_s_at
rc_H32966_at
Participates
as a member of
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
as a component of
TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] (Rattus norvegicus)
TRAF2:cIAP1,2 [cytosol] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:p-S357-RIPK1 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
as an input of
TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Rattus norvegicus)
Other forms of this molecule
Traf2 [nucleoplasm]
Traf2 [nucleoplasm]
Traf2 [cytosol]
Traf2 [cytosol]
Inferred From
TRAF2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006233656.1
,
XP_008759810.1
,
NP_001101285.1
Ensembl
ENSRNOT00000008253
,
ENSRNOG00000006238
,
ENSRNOP00000008253
RGD
1310457
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