Reactome | TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-9793672] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9793680] OPTN binds polyUb-RIPK1 within the TNFR1 complex - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10054131
displayName	TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]
hasMember	[Complex:R-MMU-9793688] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] - Mus musculus [Complex:R-MMU-5357749] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] - Mus musculus [Complex:R-MMU-9817363] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] - Mus musculus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Homo sapiens
maxDepth	7
name	TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC
schemaClass	DefinedSet
species	[Species:48892] Mus musculus
stId	R-MMU-9793686

(input)	[Reaction:R-MMU-9793680] OPTN binds polyUb-RIPK1 within the TNFR1 complex
(hasComponent)	[Complex:R-MMU-9793672] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane]
(inferredTo)	[DefinedSet:R-HSA-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]

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