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TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]
Stable Identifier
R-MMU-9793686
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
OPTN binds polyUb-RIPK1 within the TNFR1 complex (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
OPTN recruits CYLD to the TNFR1 complex (Mus musculus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNFR1-induced NF-kappa-B signaling pathway (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
Participants
members
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane]
(Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane]
(Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane]
(Mus musculus)
Participates
as an input of
OPTN binds polyUb-RIPK1 within the TNFR1 complex (Mus musculus)
as a component of
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
Inferred From
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]
(Homo sapiens)
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