Reactome | TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]

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TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9793672] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9793680] OPTN binds polyUb-RIPK1 within the TNFR1 complex - Homo sapiens
created	[InstanceEdit:9793675] Shamovsky, Veronica, 2022-06-23
dbId	9793686
displayName	TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane]
hasMember	[Complex:R-HSA-9793688] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] - Homo sapiens [Complex:R-HSA-5357749] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] - Homo sapiens [Complex:R-HSA-9817363] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Mus musculus [DefinedSet:R-RNO-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Rattus norvegicus [DefinedSet:R-CFA-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Canis familiaris [DefinedSet:R-BTA-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Bos taurus [DefinedSet:R-SSC-9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Sus scrofa [GenomeEncodedEntity:R-DRE-9793686] Ghost homologue of TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - Danio rerio
maxDepth	7
modified	[InstanceEdit:9820396] Shamovsky, Veronica, 2022-11-07
name	TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9793686
updateTrackers	[UpdateTracker:9905180] Update Tracker - [DefinedSet:9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - v83:[addHasMember, modifyName] [UpdateTracker:9928662] Update Tracker - [DefinedSet:9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - v91:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9905180] Update Tracker - [DefinedSet:9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - v83:[addHasMember, modifyName] [UpdateTracker:9928662] Update Tracker - [DefinedSet:9793686] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] - v91:[updateContainedMemberOrCandidate]
(hasComponent)	[Complex:R-HSA-9793672] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane]
(input)	[Reaction:R-HSA-9793680] OPTN binds polyUb-RIPK1 within the TNFR1 complex

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