Reactome | phospho-Pxn [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-8848613] p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] - Mus musculus [Complex:R-MMU-5218756] VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-8848611] Phosphorylated PXN recruits the CRK complex - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10052841
displayName	phospho-Pxn [cytosol]
endCoordinate	591
hasModifiedResidue	[ModifiedResidue:10052838] O4'-phospho-L-tyrosine at 31 (in Homo sapiens) [ModifiedResidue:10052839] O4'-phospho-L-tyrosine at 118 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5218693] p-Y31,Y118-PXN [cytosol] - Homo sapiens
maxDepth	1
name	phospho-Pxn p-Y31,Y118-PXN Q8VI36
producedByEvent	[Reaction:R-MMU-8848606] PTK6 phosphorylates PXN - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:Q8VI36] UniProt:Q8VI36
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-5218693
startCoordinate	1

(hasComponent)	[Complex:R-MMU-5218756] VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] [Complex:R-MMU-8848613] p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol]
(input)	[Reaction:R-MMU-8848611] Phosphorylated PXN recruits the CRK complex
(output)	[Reaction:R-MMU-8848606] PTK6 phosphorylates PXN
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5218693] p-Y31,Y118-PXN [cytosol]

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