Reactome | InlA [peptidoglycan-based cell wall]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:25409] peptidoglycan-based cell wall
componentOf	[Complex:R-HSA-8877012] InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1 [plasma membrane] - Homo sapiens [Complex:R-HSA-8876999] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8876497] InlA binds CDH1 - Homo sapiens
created	[InstanceEdit:8876503] Orlic-Milacic, Marija, 2016-06-15
dbId	8876505
displayName	InlA [peptidoglycan-based cell wall]
endCoordinate	770
inDisease	false
maxDepth	1
modified	[InstanceEdit:9836317] D'Eustachio, Peter, 2023-05-25
name	InlA Internalin A Internalin-A Internalin
referenceEntity	[ReferenceGeneProduct:uniprot:P0DJM0] UniProt:P0DJM0 inlA
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:8875362] Listeria monocytogenes
stId	R-LMO-8876505
startCoordinate	36
updateTrackers	[UpdateTracker:9906163] Update Tracker - [EntityWithAccessionedSequence:8876505] InlA [peptidoglycan-based cell wall] - v86:[add_removeCompartment]

(updatedInstance)	[UpdateTracker:9906163] Update Tracker - [EntityWithAccessionedSequence:8876505] InlA [peptidoglycan-based cell wall] - v86:[add_removeCompartment]
(entityOnOtherCell)	[Complex:R-HSA-8877010] InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] [Complex:R-HSA-8877012] InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1 [plasma membrane] [Reaction:R-HSA-8877003] CBLL1 ubiqutinates the InlA-bound CDH1 complex [Complex:R-HSA-8876983] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] [Complex:R-HSA-8876999] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] [Reaction:R-HSA-8876993] CBLL1 binds SRC-phosphorylated CDH1 complex [Reaction:R-HSA-8876497] InlA binds CDH1 [BlackBoxEvent:R-HSA-112333] SRC autophosphorylation is positively regulated by InlA-bound CDH1 [Complex:R-HSA-8876941] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CTNND1 [plasma membrane] [Complex:R-HSA-8876504] InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] [BlackBoxEvent:R-HSA-8876948] SRC phosphorylates InlA-bound CDH1 and CTNNB1
(hasComponent)	[Complex:R-HSA-8877012] InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1 [plasma membrane] [Complex:R-HSA-8876999] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] [Complex:R-HSA-8876941] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CTNND1 [plasma membrane] [Complex:R-HSA-8876504] InlA:CDH1:CTNNB1:CTNND1 [plasma membrane]
(input)	[Reaction:R-HSA-8876497] InlA binds CDH1