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InlA [peptidoglycan-based cell wall]
Stable Identifier
R-LMO-8876505
Type
Protein [EntityWithAccessionedSequence]
Species
Listeria monocytogenes
Compartment
peptidoglycan-based cell wall
Synonyms
Internalin A, Internalin-A, Internalin
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Listeria monocytogenes entry into host cells (Homo sapiens)
InlA-mediated entry of Listeria monocytogenes into host cells (Homo sapiens)
CBLL1 binds SRC-phosphorylated CDH1 complex (Homo sapiens)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] (Homo sapiens)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
CBLL1 ubiqutinates the InlA-bound CDH1 complex (Homo sapiens)
InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] (Homo sapiens)
InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] (Homo sapiens)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
InlA binds CDH1 (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
SRC autophosphorylation is positively regulated by InlA-bound CDH1 (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
InlA [peptidoglycan-based cell wall] (Listeria monocytogenes)
External Reference Information
External Reference
UniProt:P0DJM0 inlA
Gene Names
inlA, lmo0433
Chain
signal peptide:1-35, chain:36-770, propeptide:771-800
Reference Genes
BioGPS Gene:985151 inlA
KEGG:lmo:lmo0433 inlA
Monarch:985151 inlA
NCBI Gene:985151 inlA
UCSC:P0DJM0 inlA
Reference Transcript
RefSeq:NZ_CP023861.1 inlA
RefSeq:NC_003210.1 inlA
Participates
as a component of
InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1 [plasma membrane] (Homo sapiens)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] (Homo sapiens)
InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
as an input of
InlA binds CDH1 (Homo sapiens)
Cross References
PDB
1O6T
,
1O6S
,
8H63
,
1O6V
,
2OMW
,
2OMT
,
2OMU
,
2OMV
,
8H62
,
8H64
,
2OMX
,
2OMZ
,
2OMY
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P12830 CDH1
8
CDH1(155-882) [plasma membrane]
(R-HSA-198003)
CDH1(751-882) [plasma membrane]
(R-HSA-202929)
CDH1(155-750) [plasma membrane]
(R-HSA-202940)
p-Y753,Y754-CDH1(155-882) [plasma membrane]
(R-HSA-8876938)
Ub-K,p-Y753,Y754-CDH1(155-882) [plasma membrane]
(R-HSA-8877002)
CDH1(701-882) [extracellular region]
(R-HSA-2534158)
CDH1(155-700) [plasma membrane]
(R-HSA-2534244)
CDH1(732-882) [plasma membrane]
(R-HSA-3827997)
0.683
3
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