Reactome | ATP-dependent release of CDT1 from the OCCM complex

Schema > Reaction > Entries

ATP-dependent release of CDT1 from the OCCM complex Show undefined attributes

authored	[InstanceEdit:9757622] Kusic-Tisma, Jelena, 2021-10-27
catalystActivity	[CatalystActivity:9749358] ATP hydrolysis activity of ORC(1-6):CDC6:origin of replication:CDT1:MCM2-7 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9749352] Orlic-Milacic, Marija, 2021-08-01
dbId	9749350
displayName	ATP-dependent release of CDT1 from the OCCM complex
edited	[InstanceEdit:9757621] Orlic-Milacic, Marija, 2021-11-03
eventOf	[Pathway:R-HSA-68867] Assembly of the pre-replicative complex - Homo sapiens
followingEvent	[Reaction:R-HSA-9749351] CDT1-mediated formation of MCM2-7 double hexamer at the replication origin - Homo sapiens
inferredFrom	[Reaction:R-SCE-9749381] ATP-dependent release of CDT1 from the OCCM complex in budding yeast - Saccharomyces cerevisiae
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-HSA-9749318] ORC(1-6):CDC6:origin of replication:CDT1:MCM2-7 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ATP-dependent release of CDT1 from the OCCM complex
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-68536] CDT1 [nucleoplasm] [Complex:R-HSA-9749356] ORC(1-6):CDC6:origin of replication:MCM2-7 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9749320] CDT1-mediated loading of MCM2-7 to replication origins - Homo sapiens
releaseDate	2021-12-08
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9749350
summation	[Summation:9749378] Based on studies in budding yeast, once the initial complex ...

Referrals

(precedingEvent)	[Reaction:R-HSA-9749351] CDT1-mediated formation of MCM2-7 double hexamer at the replication origin
(hasEvent)	[Pathway:R-HSA-68867] Assembly of the pre-replicative complex
(inferredTo)	[Reaction:R-SCE-9749381] ATP-dependent release of CDT1 from the OCCM complex in budding yeast

Cite Us!