Reactome | SARS-CoV-2 3CLpro dimer binds to STING

Schema > Reaction > Entries

SARS-CoV-2 3CLpro dimer binds to STING Show undefined attributes

authored	[InstanceEdit:9729750] Stephan, Ralf, 2021-05-03
category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:9730519] Stephan, Ralf, 2021-05-07
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9730501
disease	[Disease:9683912] COVID-19
displayName	SARS-CoV-2 3CLpro dimer binds to STING
edited	[InstanceEdit:9766200] Shamovsky, Veronica, 2022-02-18
eventOf	[Pathway:R-HSA-9705671] SARS-CoV-2 activates/modulates innate and adaptive immune responses - Homo sapiens
input	[Complex:R-COV-9694407] 3CLp dimer [cytosol] [EntityWithAccessionedSequence:R-HSA-1834940] STING [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9730512] Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SARS-CoV-2 3CLpro dimer binds to STING
output	[Complex:R-HSA-9730518] STING:3CLpro dimer [cytosol]
precedingEvent	[Reaction:R-HSA-9694333] 3CLp forms a homodimer - Homo sapiens
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2022-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9766195] Messina, Francesco, 2022-02-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9730501
summation	[Summation:9730498] STING is a facilitator of innate immune signaling that acts ...

Referrals

(hasEvent)

[Pathway:R-HSA-9705671] SARS-CoV-2 activates/modulates innate and adaptive immune responses

Cite Us!