Reactome | E pentamer is transported to the Golgi

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E pentamer is transported to the Golgi Show undefined attributes

authored	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
category	uncertain
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:20699] Golgi membrane
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9694294
disease	[Disease:9683912] COVID-19
displayName	E pentamer is transported to the Golgi
edited	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
eventOf	[Pathway:R-HSA-9694493] Maturation of protein E - Homo sapiens
followingEvent	[Reaction:R-HSA-9705681] MPP5 binds SARS-CoV-2 E pentamer - Homo sapiens [Reaction:R-HSA-9754644] SARS-CoV-2 E pentamer binds TJP1 - Homo sapiens [Reaction:R-HSA-9754616] SARS-CoV-2 E pentamer transports Ca2+ - Homo sapiens [Reaction:R-HSA-9694444] E and N are recruited to the M lattice - Homo sapiens
input	[Complex:R-COV-9694787] Ub-3xPalmC-E pentamer [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9683049] Identification of a Golgi complex-targeting signal in the cytoplasmic tail of the severe acute respiratory syndrome coronavirus envelope protein [LiteratureReference:9682870] Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein [LiteratureReference:9756346] The envelope protein of SARS-CoV-2 increases intra-Golgi pH and forms a cation channel that is regulated by pH [LiteratureReference:9756350] Recombinant SARS-CoV-2 envelope protein traffics to the trans-Golgi network following amphipol-mediated delivery into human cells
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E pentamer is transported to the Golgi
output	[Complex:R-COV-9694408] Ub-3xPalmC-E pentamer [Golgi membrane]
precedingEvent	[Reaction:R-HSA-9694452] Protein E forms a homopentamer - Homo sapiens
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2020-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9694294
summation	[Summation:9756342] The small envelope protein (E) of the coronavirus SARS?CoV?2...
updateTrackers	[UpdateTracker:9775372] Update Tracker - [BlackBoxEvent:9694294] E pentamer is transported to the Golgi - v79:[addLiteratureReference, add_removeSummation]

Referrals

(updatedInstance)	[UpdateTracker:9775372] Update Tracker - [BlackBoxEvent:9694294] E pentamer is transported to the Golgi - v79:[addLiteratureReference, add_removeSummation]
(hasEvent)	[Pathway:R-HSA-9694493] Maturation of protein E
(precedingEvent)	[Reaction:R-HSA-9705681] MPP5 binds SARS-CoV-2 E pentamer [Reaction:R-HSA-9754644] SARS-CoV-2 E pentamer binds TJP1 [Reaction:R-HSA-9754616] SARS-CoV-2 E pentamer transports Ca2+ [Reaction:R-HSA-9694444] E and N are recruited to the M lattice