Reactome | IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane]

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IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:9666695] protein tyrosine kinase activity of IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9666421] IgG:Leishmania surface:FCGR3Ap-CD3 dimers:p-6Y-SYK:VAV1,2,3:PI(3,4,5)P3 [plasma membrane] - Homo sapiens [Complex:R-HSA-9666431] IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:CRKII:DOCK180:ELMO [plasma membrane] - Homo sapiens [Complex:R-HSA-9664277] IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-3Y-PLCG [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9666426] CRKII:DOCK180:ELMO binds FCGR3A - Homo sapiens [Reaction:R-HSA-9666435] VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK - Homo sapiens [Reaction:R-HSA-9664270] Recruitment of PLCgamma to membrane due to FCGR3A effect - Homo sapiens
created	[InstanceEdit:9664264] Murillo, Julieth, 2019-10-22
dbId	9664265
displayName	IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane]
hasComponent	[Complex:R-HSA-9664282] IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] [EntityWithAccessionedSequence:R-HSA-1861712] p-6Y-SYK [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	9
modified	[InstanceEdit:9677019] Murillo, Julieth, 2020-02-25
name	IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK
producedByEvent	[Reaction:R-HSA-9664261] Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK - Homo sapiens [Reaction:R-HSA-9664271] Release of PLCG from FCGR3A - Homo sapiens
relatedSpecies	[Species:9658193] Leishmania major
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9664265
updateTrackers	[UpdateTracker:9953763] Update Tracker - [Complex:9664265] IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] - v93:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9953763] Update Tracker - [Complex:9664265] IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] - v93:[updateContainedComponent]
(input)	[Reaction:R-HSA-9666426] CRKII:DOCK180:ELMO binds FCGR3A [Reaction:R-HSA-9666435] VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK [Reaction:R-HSA-9664270] Recruitment of PLCgamma to membrane due to FCGR3A effect
(hasComponent)	[Complex:R-HSA-9666431] IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:CRKII:DOCK180:ELMO [plasma membrane] [Complex:R-HSA-9666421] IgG:Leishmania surface:FCGR3Ap-CD3 dimers:p-6Y-SYK:VAV1,2,3:PI(3,4,5)P3 [plasma membrane] [Complex:R-HSA-9666423] IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-VAV1,2,3:PI(3,4,5)P3 [plasma membrane] [Complex:R-HSA-9664266] IgG:Leishmania surface:p-FCGR3As:p-6Y-SYK:PLCG [plasma membrane] [Complex:R-HSA-9664277] IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-3Y-PLCG [plasma membrane]
(physicalEntity)	[CatalystActivity:9666695] protein tyrosine kinase activity of IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane]
(output)	[Reaction:R-HSA-9664261] Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK [Reaction:R-HSA-9664271] Release of PLCG from FCGR3A