Reactome | AMPK phosphorylates MAPT

Schema > Reaction > Entries

authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
catalystActivity	[CatalystActivity:9619530] protein serine/threonine kinase activity of p-AMPK heterotrimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9619514] Orlic-Milacic, Marija, 2018-09-17
dbId	9619515
displayName	AMPK phosphorylates MAPT
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-9619483] Activation of AMPK downstream of NMDARs - Homo sapiens
inferredFrom	[Reaction:R-NUL-9619534] AMPK phosphorylates Mapt - Rattus norvegicus
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-HSA-9619519] MAPT-8 [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AMPK phosphorylates MAPT
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-HSA-9619521] p-S262,S356,S396-MAPT-8 [cytosol]
precedingEvent	[Reaction:R-HSA-9619478] CAMKK2 phosphorylates AMPK - Homo sapiens
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9619515
summation	[Summation:9619532] AMPK, activated by CAMKK2-mediated phosphorylation, phosphor...

(hasEvent)	[Pathway:R-HSA-9619483] Activation of AMPK downstream of NMDARs
(inferredTo)	[Reaction:R-NUL-9619534] AMPK phosphorylates Mapt

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