Reactome | CAMKK2 phosphorylates AMPK

Schema > Reaction > Entries

authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
catalystActivity	[CatalystActivity:9619402] calcium/calmodulin-dependent protein kinase activity of p-CAMKK2:CALM1:4xCa2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9619477] Orlic-Milacic, Marija, 2018-09-17
dbId	9619478
displayName	CAMKK2 phosphorylates AMPK
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-9619483] Activation of AMPK downstream of NMDARs - Homo sapiens
followingEvent	[Reaction:R-HSA-9619515] AMPK phosphorylates MAPT - Homo sapiens
inferredFrom	[Reaction:R-NUL-9619488] Camkk2 phosphorylates AMPK - Rattus norvegicus
input	[Complex:R-HSA-380961] AMPK heterotrimer [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CAMKK2 phosphorylates AMPK
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-380934] p-AMPK heterotrimer [cytosol]
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9619478
summation	[Summation:9619487] Activated CAMKK2 (CaMKK-beta) phosphorylates the alpha subun...

(precedingEvent)	[Reaction:R-HSA-9619515] AMPK phosphorylates MAPT
(hasEvent)	[Pathway:R-HSA-9619483] Activation of AMPK downstream of NMDARs
(inferredTo)	[Reaction:R-NUL-9619488] Camkk2 phosphorylates AMPK

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