Reactome | IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5

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IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 Show undefined attributes

authored	[InstanceEdit:9014992] Duenas, Corina, 2017-08-07
category	uncertain
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8983388] Duenas, Corina, 2017-03-23
dbId	8983378
displayName	IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5
edited	[InstanceEdit:9015191] Duenas, Corina, 2017-08-09
eventOf	[Pathway:R-HSA-8983432] Interleukin-15 signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8983371] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 - Homo sapiens
input	[Complex:R-HSA-9009701] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] [CandidateSet:R-HSA-9007142] STAT3,STAT5,(STAT3:STAT5) [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:539064] Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15
maxDepth	1
modified	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
name	IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5
orthologousEvent	[BlackBoxEvent:R-SSC-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 - Sus scrofa [BlackBoxEvent:R-BTA-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 - Bos taurus [BlackBoxEvent:R-CFA-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 - Canis familiaris [BlackBoxEvent:R-RNO-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 - Rattus norvegicus [BlackBoxEvent:R-MMU-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 - Mus musculus
output	[Complex:R-HSA-8983118] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9009700] IL2RB and IL2RG are phosphorylated - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-8983378
summation	[Summation:8983297] Signal transducer and activator of transcription 3 (STAT3), ...

Referrals

(hasEvent)	[Pathway:R-HSA-8983432] Interleukin-15 signaling
(precedingEvent)	[BlackBoxEvent:R-HSA-8983371] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5

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