Reactome | IL2RB and IL2RG are phosphorylated

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IL2RB and IL2RG are phosphorylated Show undefined attributes

authored	[InstanceEdit:9014992] Duenas, Corina, 2017-08-07
category	uncertain
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:9009728] Duenas, Corina, 2017-06-22
dbId	9009700
displayName	IL2RB and IL2RG are phosphorylated
edited	[InstanceEdit:9015191] Duenas, Corina, 2017-08-09
eventOf	[Pathway:R-HSA-8983432] Interleukin-15 signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8983299] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds SHC1 - Homo sapiens [BlackBoxEvent:R-HSA-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9009867] Il2rb and Il2rg are phosphorylated - Mus musculus
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-8983138] IL15:IL15RA:IL2RB:p-Y-JAK1:IL2RG:p-JAK3 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL2RB and IL2RG are phosphorylated
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-9009701] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-8983300] IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9009700
summation	[Summation:9009699] Inferred from mouse: Interleukin-2 receptor subunit beta (IL...
updateTrackers	[UpdateTracker:9780194] Update Tracker - [BlackBoxEvent:9009700] IL2RB and IL2RG are phosphorylated - v63:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780194] Update Tracker - [BlackBoxEvent:9009700] IL2RB and IL2RG are phosphorylated - v63:[modifyText]
(hasEvent)	[Pathway:R-HSA-8983432] Interleukin-15 signaling
(precedingEvent)	[BlackBoxEvent:R-HSA-8983299] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds SHC1 [BlackBoxEvent:R-HSA-8983378] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5
(inferredTo)	[BlackBoxEvent:R-MMU-9009867] Il2rb and Il2rg are phosphorylated

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