Signal transducer and activator of transcription 3 (STAT3), ...

created [InstanceEdit:8983295] Duenas, Corina, 2017-03-23
dbId 8983297
displayName Signal transducer and activator of transcription 3 (STAT3), ...
literatureReference
modified [InstanceEdit:9014989] Duenas, Corina, 2017-08-07
schemaClass Summation
text Signal transducer and activator of transcription 3 (STAT3), Signal transducer and activator of transcription 5A and 5B (STAT5) are believed to bind the Interleukin-15 (IL15) receptor complex, which consists of IL15, Interleukin-15 receptor alpha subunit (IL15RA, IL15R?), Interleukin-2 receptor beta subunit (IL2RB, IL2R?), which is associated with JAK1 and Interleukin receptor gamma subunit, which is associated with JAK3 (Johnston et al. 1995). This is a black-box event because STAT binding is inferred from their subsequent phosphorylation.
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