Reactome | 1,25(OH)2D translocates from cytosol to nucleoplasm

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:8963914] Jassal, Bijay, 2017-02-14
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:8963914] Jassal, Bijay, 2017-02-14
dbId	8963913
displayName	1,25(OH)2D translocates from cytosol to nucleoplasm
edited	[InstanceEdit:8963914] Jassal, Bijay, 2017-02-14
eventOf	[Pathway:R-HSA-196791] Vitamin D (calciferol) metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-8963915] 1,25(OH)2D binds VDR - Homo sapiens [Reaction:R-HSA-4546387] PIAS4 SUMOylates VDR with SUMO2 - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:1122] lipid transport
input	[SimpleEntity:R-ALL-209800] 1,25(OH)2D [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8963930] Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects
maxDepth	1
modified	[InstanceEdit:9959973] D'Eustachio, Peter, 2025-07-03
name	1,25(OH)2D translocates from cytosol to nucleoplasm
output	[SimpleEntity:R-ALL-8963912] 1,25(OH)2D [nucleoplasm]
precedingEvent	[Reaction:R-HSA-209868] CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D - Homo sapiens
releaseDate	2017-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9028766] Holick, Michael, 2017-11-09
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-8963913
summation	[Summation:8963940] The biologically active form of vitamin D, 1-alpha, 25-dihyd...

(hasEvent)	[Pathway:R-HSA-196791] Vitamin D (calciferol) metabolism
(precedingEvent)	[Reaction:R-HSA-8963915] 1,25(OH)2D binds VDR [Reaction:R-HSA-4546387] PIAS4 SUMOylates VDR with SUMO2

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