Reactome | SLC35D2 exchanges UDP-GlcNAc for UMP

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SLC35D2 exchanges UDP-GlcNAc for UMP Show undefined attributes

authored	[InstanceEdit:744238] Jassal, Bijay, 2010-05-17
catalystActivity	[CatalystActivity:744232] nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane]
catalystActivityReference	[CatalystActivityReference:9792604] nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane] Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:744238] Jassal, Bijay, 2010-05-17
crossReference	[DatabaseIdentifier:12668075] RHEA:72695 [DatabaseIdentifier:9941483] RHEA:72695
dbId	744231
displayName	SLC35D2 exchanges UDP-GlcNAc for UMP
edited	[InstanceEdit:744238] Jassal, Bijay, 2010-05-17
eventOf	[Pathway:R-HSA-2022928] HS-GAG biosynthesis - Homo sapiens [Pathway:R-HSA-727802] Transport of nucleotide sugars - Homo sapiens
followingEvent	[Reaction:R-HSA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG - Homo sapiens [Reaction:R-HSA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker - Homo sapiens [Reaction:R-HSA-2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:25012] nucleotide-sugar transmembrane transport
input	[SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol] [SimpleEntity:R-ALL-735698] UMP [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:744226] Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection [LiteratureReference:744228] Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	SLC35D2 exchanges UDP-GlcNAc for UMP
orthologousEvent	[Reaction:R-BTA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Bos taurus [Reaction:R-DDI-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Dictyostelium discoideum [Reaction:R-CEL-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Caenorhabditis elegans [Reaction:R-DME-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Drosophila melanogaster [Reaction:R-GGA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Gallus gallus [Reaction:R-XTR-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Xenopus tropicalis [Reaction:R-SSC-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Sus scrofa [Reaction:R-CFA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Canis familiaris [Reaction:R-RNO-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Rattus norvegicus [Reaction:R-MMU-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Mus musculus
output	[SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen] [SimpleEntity:R-ALL-109402] UMP [cytosol]
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:706449] He, L, 2010-05-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-744231
summation	[Summation:744884] The human gene SLC35D2 encodes the UDP-N-acetylglucosamine/U...
updateTrackers	[UpdateTracker:9847051] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-GlcNAc for UMP - v82:[add_removeInput, add_removeOutput, modifyText] [UpdateTracker:9953558] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-GlcNAc for UMP - v93:[modifyText] [UpdateTracker:9787459] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-sugars for UMP - v45:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9847051] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-GlcNAc for UMP - v82:[add_removeInput, add_removeOutput, modifyText] [UpdateTracker:9953558] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-GlcNAc for UMP - v93:[modifyText] [UpdateTracker:9787459] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-sugars for UMP - v45:[modifyText]
(hasEvent)	[Pathway:R-HSA-727802] Transport of nucleotide sugars [Pathway:R-HSA-2022928] HS-GAG biosynthesis [Pathway:R-HSA-2022854] Keratan sulfate biosynthesis
(precedingEvent)	[Reaction:R-HSA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG [Reaction:R-HSA-2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain [Reaction:R-HSA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker

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