Reactome | SLC35D2 exchanges UDP-GlcNAc for UMP

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SLC35D2 exchanges UDP-GlcNAc for UMP Show undefined attributes

catalystActivity	[CatalystActivity:10239920] nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10239924
displayName	SLC35D2 exchanges UDP-GlcNAc for UMP
eventOf	[Pathway:R-BTA-2022928] HS-GAG biosynthesis - Bos taurus [Pathway:R-BTA-2022854] Keratan sulfate biosynthesis - Bos taurus [Pathway:R-BTA-727802] Transport of nucleotide sugars - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-2022919] EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue - Bos taurus [Reaction:R-BTA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG - Bos taurus
inferredFrom	[Reaction:R-HSA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Homo sapiens
input	[SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol] [SimpleEntity:R-ALL-735698] UMP [Golgi lumen]
isInDisease	false
isInferred	true
name	SLC35D2 exchanges UDP-GlcNAc for UMP
output	[SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen] [SimpleEntity:R-ALL-109402] UMP [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-744231
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-727802] Transport of nucleotide sugars [Pathway:R-BTA-2022928] HS-GAG biosynthesis [Pathway:R-BTA-2022854] Keratan sulfate biosynthesis
(precedingEvent)	[Reaction:R-BTA-2022919] EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue [Reaction:R-BTA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG
(inferredTo)	[Reaction:R-HSA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP