Reactome | SLC35D2 exchanges UDP-GlcNAc for UMP

Schema > Reaction > Entries

SLC35D2 exchanges UDP-GlcNAc for UMP Show undefined attributes

catalystActivity	[CatalystActivity:10260530] nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10260534
displayName	SLC35D2 exchanges UDP-GlcNAc for UMP
eventOf	[Pathway:R-CFA-2022928] HS-GAG biosynthesis - Canis familiaris [Pathway:R-CFA-727802] Transport of nucleotide sugars - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG - Canis familiaris [Reaction:R-CFA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker - Canis familiaris [Reaction:R-CFA-2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain - Canis familiaris
goBiologicalProcess	[GO_BiologicalProcess:25012] nucleotide-sugar transmembrane transport
inferredFrom	[Reaction:R-HSA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP - Homo sapiens
input	[SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol] [SimpleEntity:R-ALL-735698] UMP [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC35D2 exchanges UDP-GlcNAc for UMP
output	[SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen] [SimpleEntity:R-ALL-109402] UMP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-744231
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-727802] Transport of nucleotide sugars [Pathway:R-CFA-2022928] HS-GAG biosynthesis [Pathway:R-CFA-2022854] Keratan sulfate biosynthesis
(precedingEvent)	[Reaction:R-CFA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG [Reaction:R-CFA-2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain [Reaction:R-CFA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker
(inferredTo)	[Reaction:R-HSA-744231] SLC35D2 exchanges UDP-GlcNAc for UMP