Reactome | SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP

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SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP Show undefined attributes

authored	[InstanceEdit:735694] Jassal, Bijay, 2010-05-13
catalystActivity	[CatalystActivity:735696] UDP-galactose transmembrane transporter activity of SLC35A2 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen [Compartment:70101] cytosol
created	[InstanceEdit:735694] Jassal, Bijay, 2010-05-13
dbId	735702
diseaseReaction	[FailedReaction:R-HSA-5652099] Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP - Homo sapiens
displayName	SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP
edited	[InstanceEdit:735694] Jassal, Bijay, 2010-05-13
eventOf	[Pathway:R-HSA-727802] Transport of nucleotide sugars - Homo sapiens
followingEvent	[Reaction:R-HSA-2046298] B4GALTs transfer Gal to a branch of keratan - Homo sapiens [Reaction:R-HSA-2025723] B4GALTs transfer Gal to the N-glycan precursor - Homo sapiens [Reaction:R-HSA-9632033] CSGALNACTs transfer GalNAc to CS chain - Homo sapiens [Reaction:R-HSA-2046265] B4GALTs transfer Gal to the keratan chain - Homo sapiens [Reaction:R-HSA-1971487] Chondroitin polymerase complex transfers GalNAc to CS chain - Homo sapiens [Reaction:R-HSA-1971482] CSGALNACTs transfer GalNAc to CS linker glycan - Homo sapiens [Reaction:R-HSA-1889978] B3GALT6 transfers Gal to the tetrasaccharide linker - Homo sapiens [Reaction:R-HSA-1889981] B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker - Homo sapiens [Reaction:R-HSA-5653878] B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac - Homo sapiens
input	[DefinedSet:R-ALL-735692] UDP-Gal, UDP-GalNAc [cytosol] [SimpleEntity:R-ALL-735698] UMP [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:735701] Human UDP-galactose translocator: molecular cloning of a complementary DNA that complements the genetic defect of a mutant cell line deficient in UDP-galactose translocator [LiteratureReference:735695] Human and Drosophila UDP-galactose transporters transport UDP-N-acetylgalactosamine in addition to UDP-galactose
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP
orthologousEvent	[Reaction:R-BTA-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Bos taurus [Reaction:R-PFA-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Plasmodium falciparum [Reaction:R-SPO-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Schizosaccharomyces pombe [Reaction:R-CEL-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Caenorhabditis elegans [Reaction:R-DME-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Drosophila melanogaster [Reaction:R-SSC-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Sus scrofa [Reaction:R-CFA-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Canis familiaris [Reaction:R-RNO-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Rattus norvegicus [Reaction:R-MMU-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Mus musculus
output	[DefinedSet:R-ALL-735691] UDP-Gal, UDP-GalNAc [Golgi lumen] [SimpleEntity:R-ALL-109402] UMP [cytosol]
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:706449] He, L, 2010-05-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-735702
summation	[Summation:735681] The human gene SLC35A2 encodes the UDP-galactose transporter...
updateTrackers	[UpdateTracker:9785178] Update Tracker - [Reaction:735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - v52:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785178] Update Tracker - [Reaction:735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - v52:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-5652099] Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP
(hasEvent)	[Pathway:R-HSA-727802] Transport of nucleotide sugars
(precedingEvent)	[Reaction:R-HSA-5653878] B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac [Reaction:R-HSA-2046298] B4GALTs transfer Gal to a branch of keratan [Reaction:R-HSA-2046265] B4GALTs transfer Gal to the keratan chain [Reaction:R-HSA-2025723] B4GALTs transfer Gal to the N-glycan precursor [Reaction:R-HSA-9632033] CSGALNACTs transfer GalNAc to CS chain [Reaction:R-HSA-1971487] Chondroitin polymerase complex transfers GalNAc to CS chain [Reaction:R-HSA-1971482] CSGALNACTs transfer GalNAc to CS linker glycan [Reaction:R-HSA-1889978] B3GALT6 transfers Gal to the tetrasaccharide linker [Reaction:R-HSA-1889981] B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker

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