Reactome | 80S ribosome [cytosol]

Schema > Complex > Entries

80S ribosome [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:159645] peptidyltransferase activity of 80S ribosome [cytosol] [CatalystActivity:159651] GTPase activity of 80S ribosome [cytosol] [CatalystActivity:192829] translation elongation factor activity of 80S ribosome [cytosol] [CatalystActivity:192666] translation elongation factor activity of 80S ribosome [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-453157] 80S Ribosome:mRNA Complex [cytosol] - Homo sapiens [Complex:R-HSA-143396] Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:tRNA Complex [cytosol] - Homo sapiens [Complex:R-HSA-927773] Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-1799335] Synthesis of nascent polypeptide containing signal sequence - Homo sapiens [Reaction:R-HSA-72673] Release of 40S and 60S subunits from the 80S ribosome - Homo sapiens [BlackBoxEvent:R-HSA-9014610] Translation of ROBO3.2 mRNA initiates NMD - Homo sapiens
dbId	72500
displayName	80S ribosome [cytosol]
hasComponent	[Complex:R-HSA-72392] 40S ribosomal complex [cytosol] [Complex:R-HSA-72499] 60S ribosomal complex [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-72500] 80S ribosome [cytosol] - Mus musculus [Complex:R-RNO-72500] 80S ribosome [cytosol] - Rattus norvegicus [Complex:R-CFA-72500] 80S ribosome [cytosol] - Canis familiaris [Complex:R-BTA-72500] 80S ribosome [cytosol] - Bos taurus [Complex:R-SSC-72500] 80S ribosome [cytosol] - Sus scrofa [Complex:R-DRE-72500] 80S ribosome [cytosol] - Danio rerio [Complex:R-XTR-72500] 80S ribosome [cytosol] - Xenopus tropicalis [Complex:R-GGA-72500] 80S ribosome [cytosol] - Gallus gallus [Complex:R-DME-72500] 80S ribosome [cytosol] - Drosophila melanogaster [Complex:R-CEL-72500] 80S ribosome [cytosol] - Caenorhabditis elegans [Complex:R-DDI-72500] 80S ribosome [cytosol] - Dictyostelium discoideum [Complex:R-SPO-72500] 80S ribosome [cytosol] - Schizosaccharomyces pombe [Complex:R-SCE-72500] 80S ribosome [cytosol] - Saccharomyces cerevisiae [Complex:R-PFA-72500] 80S ribosome [cytosol] - Plasmodium falciparum
modified	[InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06
name	80S ribosome 80S monosome
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-72500

Referrals

(hasComponent)	[Complex:R-HSA-143396] Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:tRNA Complex [cytosol] [Complex:R-HSA-927773] Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] [Complex:R-HSA-927787] Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] [Complex:R-HSA-9014609] Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] [Complex:R-HSA-453157] 80S Ribosome:mRNA Complex [cytosol] [Complex:R-HSA-141952] 80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] [Complex:R-HSA-156927] Elongation complex with growing peptide chain [cytosol] [Complex:R-HSA-1799325] membrane-bound ribosome:mRNA:cleaved polypeptide [endoplasmic reticulum membrane] [Complex:R-HSA-1799336] membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] [Complex:R-HSA-1799327] ribosome:mRNA:polypeptide+signal [cytosol] [Complex:R-HSA-72504] 80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] [Complex:R-HSA-72505] 80S:Met-tRNAi:mRNA [cytosol]
(input)	[BlackBoxEvent:R-HSA-9014610] Translation of ROBO3.2 mRNA initiates NMD [BlackBoxEvent:R-HSA-1799335] Synthesis of nascent polypeptide containing signal sequence [Reaction:R-HSA-72673] Release of 40S and 60S subunits from the 80S ribosome
(physicalEntity)	[CatalystActivity:159645] peptidyltransferase activity of 80S ribosome [cytosol] [CatalystActivity:159651] GTPase activity of 80S ribosome [cytosol] [CatalystActivity:192829] translation elongation factor activity of 80S ribosome [cytosol] [CatalystActivity:192666] translation elongation factor activity of 80S ribosome [cytosol]

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