Reactome | Cdc6 protein is phosphorylated by CDK

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Cdc6 protein is phosphorylated by CDK Show undefined attributes

catalystActivity	[CatalystActivity:9032216] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
dbId	69005
displayName	Cdc6 protein is phosphorylated by CDK
eventOf	[Pathway:R-HSA-69017] CDK-mediated phosphorylation and removal of Cdc6 - Homo sapiens
followingEvent	[Reaction:R-HSA-69006] Phosphorylated Cdc6 is exported from the nucleus - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-68542] CDC6 [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:68381] Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	Cdc6 protein is phosphorylated by CDK
orthologousEvent	[Reaction:R-RNO-69005] Cdc6 protein is phosphorylated by CDK - Rattus norvegicus [Reaction:R-SPO-69005] Cdc6 protein is phosphorylated by CDK - Schizosaccharomyces pombe [Reaction:R-DDI-69005] Cdc6 protein is phosphorylated by CDK - Dictyostelium discoideum [Reaction:R-CEL-69005] Cdc6 protein is phosphorylated by CDK - Caenorhabditis elegans [Reaction:R-DME-69005] Cdc6 protein is phosphorylated by CDK - Drosophila melanogaster [Reaction:R-GGA-69005] Cdc6 protein is phosphorylated by CDK - Gallus gallus [Reaction:R-XTR-69005] Cdc6 protein is phosphorylated by CDK - Xenopus tropicalis [Reaction:R-DRE-69005] Cdc6 protein is phosphorylated by CDK - Danio rerio [Reaction:R-SSC-69005] Cdc6 protein is phosphorylated by CDK - Sus scrofa [Reaction:R-BTA-69005] Cdc6 protein is phosphorylated by CDK - Bos taurus [Reaction:R-CFA-69005] Cdc6 protein is phosphorylated by CDK - Canis familiaris [Reaction:R-MMU-69005] Cdc6 protein is phosphorylated by CDK - Mus musculus
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5661317] p-CDC6 [nucleoplasm]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-69005
summation	[Summation:178530] At the beginning of this reaction, 1 molecule of 'CDC6', and...
updateTrackers	[UpdateTracker:9785388] Update Tracker - [Reaction:69005] Cdc6 protein is phosphorylated by CDK - v52:[add_removeOutput] [UpdateTracker:9779941] Update Tracker - [Reaction:69005] Cdc6 protein is phosphorylated by CDK - v64:[add_removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9785388] Update Tracker - [Reaction:69005] Cdc6 protein is phosphorylated by CDK - v52:[add_removeOutput] [UpdateTracker:9779941] Update Tracker - [Reaction:69005] Cdc6 protein is phosphorylated by CDK - v64:[add_removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-69017] CDK-mediated phosphorylation and removal of Cdc6
(precedingEvent)	[Reaction:R-HSA-69006] Phosphorylated Cdc6 is exported from the nucleus

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