Reactome | CDC6 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

CDC6 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9749216] ORC(1-6):CDC6:origin of replication [nucleoplasm] - Homo sapiens [Complex:R-HSA-9749213] CDC6:MCM8 [nucleoplasm] - Homo sapiens [Complex:R-HSA-157563] pre-replicative complex (Orc1-minus) [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-69005] Cdc6 protein is phosphorylated by CDK - Homo sapiens [Reaction:R-HSA-9749215] MCM8 binds CDC6 - Homo sapiens [Reaction:R-HSA-68688] CDC6 association with ORC(1-6) at replication origins - Homo sapiens
dbId	68542
deleted	[Deleted:5661321] Deletion of instance: 113574
displayName	CDC6 [nucleoplasm]
endCoordinate	560
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-68542] CDC6 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-68542] Cdc6 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-68542] CDC6 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-68542] CDC6 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-68542] CDC6 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-68542] cdc6 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-68542] cdc6 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-68542] CDC6 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-68542] CDC6 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-68542] cdc-6 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-68542] CDC6 [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-68542] CDC6 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-68542] CDC6 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-68542] CDC6 [nucleoplasm] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:73680] Gillespie, ME, 0000-00-00 00:00:00
name	CDC6
producedByEvent	[BlackBoxEvent:R-HSA-8961619] CDC6 gene expression is stimulated by E2F1 and repressed by the DREAM complex - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q99741] UniProt:Q99741 CDC6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-68542
startCoordinate	1
updateTrackers	[UpdateTracker:9878110] Update Tracker - [EntityWithAccessionedSequence:68542] CDC6 [nucleoplasm] - v44:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9878110] Update Tracker - [EntityWithAccessionedSequence:68542] CDC6 [nucleoplasm] - v44:[modifyEndCoordinate]
(replacementInstances)	[Deleted:5661321] Deletion of instance: 113574
(input)	[Reaction:R-HSA-69005] Cdc6 protein is phosphorylated by CDK [Reaction:R-HSA-9749215] MCM8 binds CDC6 [Reaction:R-HSA-68688] CDC6 association with ORC(1-6) at replication origins
(hasComponent)	[Complex:R-HSA-157563] pre-replicative complex (Orc1-minus) [nucleoplasm] [Complex:R-HSA-9749213] CDC6:MCM8 [nucleoplasm] [Complex:R-HSA-9749216] ORC(1-6):CDC6:origin of replication [nucleoplasm] [Complex:R-HSA-68543] CDC6:ORC:origin complex [nucleoplasm]
(activeUnit)	[CatalystActivity:9749358] ATP hydrolysis activity of ORC(1-6):CDC6:origin of replication:CDT1:MCM2-7 [nucleoplasm]
(output)	[BlackBoxEvent:R-HSA-8961619] CDC6 gene expression is stimulated by E2F1 and repressed by the DREAM complex

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