Cdc6 protein is phosphorylated by CDK

Stable Identifier
R-HSA-69005
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'CDC6', and 1 molecule of 'ATP' are present. At the end of this reaction, 1 molecule of 'ADP', and 1 molecule of 'phosphorylated Cdc6' are present.

This reaction takes place in the 'nucleus' and is mediated by the 'kinase activity' of 'CDK'.

Literature References
PubMed ID Title Journal Year
10339564 Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6.

Jiang, W, Wells, NJ, Hunter, T

Proc Natl Acad Sci U S A 1999
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm]
Physical Entity
Activity
Orthologous Events