Reactome | Cdc6 protein is phosphorylated by CDK

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Cdc6 protein is phosphorylated by CDK Show undefined attributes

catalystActivity	[CatalystActivity:10732870] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10732872
displayName	Cdc6 protein is phosphorylated by CDK
eventOf	[Pathway:R-GGA-69017] CDK-mediated phosphorylation and removal of Cdc6 - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-69006] Phosphorylated Cdc6 is exported from the nucleus - Gallus gallus
inferredFrom	[Reaction:R-HSA-69005] Cdc6 protein is phosphorylated by CDK - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-68542] CDC6 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Cdc6 protein is phosphorylated by CDK
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-5661317] phospho-CDC6 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-69005
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-69017] CDK-mediated phosphorylation and removal of Cdc6
(precedingEvent)	[Reaction:R-GGA-69006] Phosphorylated Cdc6 is exported from the nucleus
(inferredTo)	[Reaction:R-HSA-69005] Cdc6 protein is phosphorylated by CDK

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