Reactome | CCND1 [cytosol]

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CCND1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-68337] CDK6:CCND1 [cytosol] - Homo sapiens
dbId	68328
displayName	CCND1 [cytosol]
endCoordinate	295
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-182561] Ccnd1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-68328] Ccnd1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-68328] CCND1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-68328] CCND1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-68328] CCND1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-68328] ccnd1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-68328] ccnd1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-68328] CCND1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-68328] CycD [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-68328] cyd-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-68328] cycA [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-68328-2] cycD [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-68328-3] Homologues of CCND1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-68328] rem1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-68328-2] crs1 [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SPO-68328-3] Homologues of CCND1 [cytosol] - Schizosaccharomyces pombe
maxDepth	1
memberOf	[CandidateSet:R-HSA-182700] Cyclin D [cytosol] - Homo sapiens
modified	[InstanceEdit:3322334] Wu, G, 2013-05-03
name	CCND1 G1/S-specific cyclin D1 PRAD1 oncogene BCL-1 oncogene
producedByEvent	[BlackBoxEvent:R-HSA-9858645] MITF-M and CTNNB1-dependent CCND1 expression - Homo sapiens [BlackBoxEvent:R-HSA-8951443] Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 - Homo sapiens [BlackBoxEvent:R-HSA-9009378] Estrogen-responsive CCND1 gene expression - Homo sapiens [BlackBoxEvent:R-HSA-9623355] ESR1-dependent CCND1 expression - Homo sapiens [BlackBoxEvent:R-HSA-8853956] Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 and inhibited by VENTX:TCF4,LEF1 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P24385] UniProt:P24385 CCND1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-68328
startCoordinate	1
updateTrackers	[UpdateTracker:9872618] Update Tracker - [EntityWithAccessionedSequence:68328] CCND1 [cytosol] - v41:[modifyEndCoordinate] [UpdateTracker:9886250] Update Tracker - [EntityWithAccessionedSequence:68328] CCND1 [cytosol] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9872618] Update Tracker - [EntityWithAccessionedSequence:68328] CCND1 [cytosol] - v41:[modifyEndCoordinate] [UpdateTracker:9886250] Update Tracker - [EntityWithAccessionedSequence:68328] CCND1 [cytosol] - v45:[addName]
(output)	[BlackBoxEvent:R-HSA-9858645] MITF-M and CTNNB1-dependent CCND1 expression [BlackBoxEvent:R-HSA-8951443] Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 [BlackBoxEvent:R-HSA-9009378] Estrogen-responsive CCND1 gene expression [BlackBoxEvent:R-HSA-9623355] ESR1-dependent CCND1 expression [BlackBoxEvent:R-HSA-8853956] Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 and inhibited by VENTX:TCF4,LEF1
(hasComponent)	[Complex:R-HSA-68337] CDK6:CCND1 [cytosol] [Complex:R-HSA-68331] CDK4:CCND1 [cytosol]
(hasMember)	[CandidateSet:R-HSA-182700] Cyclin D [cytosol]

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