Reactome | TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]

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TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-6782134] TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-6782138] ERCC5 and RPA bind TC-NER site - Homo sapiens
created	[InstanceEdit:6782121] Orlic-Milacic, Marija, 2015-06-04
dbId	6782111
displayName	TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-65748] TCEA1 [nucleoplasm] [Complex:R-HSA-6782122] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] [Complex:R-HSA-6781845] UVSSA:USP7 [nucleoplasm] [Complex:R-HSA-6781957] XAB2 complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-67437] XPA [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Mus musculus [Complex:R-RNO-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Canis familiaris [Complex:R-BTA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Bos taurus [Complex:R-SSC-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Sus scrofa [Complex:R-DRE-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Danio rerio [Complex:R-XTR-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Gallus gallus [Complex:R-DME-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Saccharomyces cerevisiae [Complex:R-PFA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Plasmodium falciparum
isChimeric	false
maxDepth	7
modified	[InstanceEdit:9862022] Orlic-Milacic, Marija, 2024-02-22
name	TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:trimmed nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300
producedByEvent	[Reaction:R-HSA-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6782111
updateTrackers	[UpdateTracker:9897032] Update Tracker - [Complex:6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - v61:[updateContainedComponent] [UpdateTracker:9893660] Update Tracker - [Complex:6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - v56:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9897032] Update Tracker - [Complex:6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - v61:[updateContainedComponent] [UpdateTracker:9893660] Update Tracker - [Complex:6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - v56:[updateContainedComponent]
(hasComponent)	[Complex:R-HSA-6782134] TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm]
(input)	[Reaction:R-HSA-6782138] ERCC5 and RPA bind TC-NER site
(output)	[Reaction:R-HSA-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER

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