Reactome | TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-6782134] TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-6782138] ERCC5 and RPA bind TC-NER site - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10065162
displayName	TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-MMU-65748] TCEA1 [nucleoplasm] [Complex:R-MMU-6782122] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] [Complex:R-MMU-6781845] UVSSA:USP7 [nucleoplasm] [Complex:R-MMU-6781957] XAB2 complex [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-67437] XPA [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Homo sapiens
maxDepth	7
name	TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA
producedByEvent	[Reaction:R-MMU-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-6782111
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-MMU-6782134] TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm]
(input)	[Reaction:R-MMU-6782138] ERCC5 and RPA bind TC-NER site
(inferredTo)	[Complex:R-HSA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
(output)	[Reaction:R-MMU-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER

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