Reactome | TCEA1 [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-167082] HIV-1 elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167193] Tat-containing elongation complex prior to separation [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782220] TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens [Complex:R-HSA-6797607] CDK12-Phosphorylated Elongation Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-167077] Recruitment of elongation factors to form HIV-1 elongation complex - Homo sapiens [Reaction:R-HSA-6782004] Assembly of the pre-incision complex in TC-NER - Homo sapiens [Reaction:R-HSA-112379] Recruitment of elongation factors to form elongation complex - Homo sapiens [Reaction:R-HSA-167196] Recruitment of elongation factors to form HIV-1 elongation complex - Homo sapiens
dbId	65748
displayName	TCEA1 [nucleoplasm]
endCoordinate	301
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-RNO-65748] Tcea1 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-MMU-65748] Tcea1 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-CFA-65748] TCEA1 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-SSC-65748] TCEA1 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-65748] tcea1 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-65748] plscr4 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-65748] TCEA1 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-65748] TfIIS [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-65748] TCEA1 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-65748] tcea1 [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-65748] tfs1 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-65748] DST1 [nucleoplasm] - Saccharomyces cerevisiae
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	TCEA1 TFIIS protein Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) Transcription elongation factor A protein 1 Transcription elongation factor S-II protein 1 Transcription elongation factor TFIIS.o
producedByEvent	[Reaction:R-HSA-113429] Elongating transcript encounters a lesion in the template - Homo sapiens [BlackBoxEvent:R-HSA-6782234] Recovery of RNA synthesis after TC-NER - Homo sapiens
referenceEntity	[ReferenceGeneProduct:65749] UniProt:P23193 TCEA1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-65748
startCoordinate	1

(hasComponent)	[Complex:R-HSA-167460] HIV-1 Tat-containing aborted elongation complex after arrest [nucleoplasm] - Homo sapiens [Complex:R-HSA-6797611] Elongation Complex at DNA Repair Genes [nucleoplasm] - Homo sapiens [Complex:R-HSA-6797607] CDK12-Phosphorylated Elongation Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782063] Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782066] TC-NER pre-incision complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-9684117] TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782222] TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782220] TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782230] TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] - Homo sapiens [Complex:R-HSA-167082] HIV-1 elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-112433] Elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-113724] Elongation complex prior to separation [nucleoplasm] - Homo sapiens [Complex:R-HSA-113726] Elongation complex with separated and uncleaved transcript [nucleoplasm] - Homo sapiens [Complex:R-HSA-113719] Processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-113720] Paused processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-113721] Arrested processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167185] HIV-1 elongation complex containing Tat [nucleoplasm] - Homo sapiens [Complex:R-HSA-167184] HIV-1 Tat-containing processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167193] Tat-containing elongation complex prior to separation [nucleoplasm] - Homo sapiens [Complex:R-HSA-167071] HIV-1 Tat-containing paused processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167091] HIV-1 Tat-containing arrested processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167199] P-TEFb(Cyclin T1:Cdk9)-containing elongation complex with separated and uncleaved transcript [nucleoplasm] - Homo sapiens [Complex:R-HSA-167081] HIV-1 processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167286] HIV-1 arrested processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167482] HIV-1 aborted elongation complex after arrest [nucleoplasm] - Homo sapiens [Complex:R-HSA-113722] Aborted elongation complex after arrest [nucleoplasm] - Homo sapiens [Complex:R-HSA-167283] HIV-1 paused processive elongation complex [nucleoplasm] - Homo sapiens
(input)	[Reaction:R-HSA-6782004] Assembly of the pre-incision complex in TC-NER - Homo sapiens [Reaction:R-HSA-167077] Recruitment of elongation factors to form HIV-1 elongation complex - Homo sapiens [Reaction:R-HSA-112379] Recruitment of elongation factors to form elongation complex - Homo sapiens [Reaction:R-HSA-167196] Recruitment of elongation factors to form HIV-1 elongation complex - Homo sapiens
(output)	[Reaction:R-HSA-113429] Elongating transcript encounters a lesion in the template - Homo sapiens [BlackBoxEvent:R-HSA-6782234] Recovery of RNA synthesis after TC-NER - Homo sapiens

TCEA1 [nucleoplasm]

Referrals