Reactome | STAT1 [cytosol]

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STAT1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] - Homo sapiens [Complex:R-HSA-8983842] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] - Homo sapiens [Complex:R-HSA-8983998] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor - Homo sapiens [BlackBoxEvent:R-HSA-8983841] STAT1 associates with IL6ST:IL6ST - Homo sapiens [BlackBoxEvent:R-HSA-8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex - Homo sapiens [Reaction:R-HSA-9008015] RUNX2 binds STAT1 - Homo sapiens [BlackBoxEvent:R-HSA-8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor - Homo sapiens
created	[InstanceEdit:629624] Garapati, P V, 2010-04-26
dbId	629622
displayName	STAT1 [cytosol]
endCoordinate	750
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-629622] Stat1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-629622] Stat1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-629622] STAT1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-629622] STAT1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-629622] STAT1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-629622] stat1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-629622] stat1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-629622] STAT1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-629622] Stat92E [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-629622] STAT1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-629622-2] sta-2 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-629622-3] sta-1 [cytosol] - Caenorhabditis elegans [DefinedSet:R-CEL-629622-4] Homologues of STAT1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-629622] dstA [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-629622-2] dstC [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-629622-3] STAT1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-629622-4] STAT1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-629622-5] STAT1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-629622-6] dstB [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-629622-7] dstD [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-629622-8] Homologues of STAT1 [cytosol] - Dictyostelium discoideum
memberOf	[DefinedSet:R-HSA-6788573] STAT1,STAT3,STAT6 [cytosol] - Homo sapiens [DefinedSet:R-HSA-9009216] STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] - Homo sapiens [DefinedSet:R-HSA-9010176] STAT1, STAT3, STAT5 [cytosol] - Homo sapiens [DefinedSet:R-HSA-9006868] STAT1,STAT3,STAT4,STAT5 [cytosol] - Homo sapiens [DefinedSet:R-HSA-1433551] STATs [cytosol] - Homo sapiens [DefinedSet:R-HSA-9729448] STAT1,STAT2 [cytosol] - Homo sapiens [DefinedSet:R-HSA-1112559] STAT1, STAT3 [cytosol] - Homo sapiens [DefinedSet:R-HSA-380756] STAT family members [cytosol] - Homo sapiens [CandidateSet:R-HSA-1169379] ISG15 targets [cytosol] - Homo sapiens [DefinedSet:R-HSA-6790032] STAT3-upregulated cytosolic proteins [cytosol] - Homo sapiens
modified	[InstanceEdit:8951035] Duenas, Corina, 2016-12-02
name	STAT1 Signal transducer and activator of transcription 1-alpha/beta STAT1_HUMAN
referenceEntity	[ReferenceGeneProduct:404006] UniProt:P42224 STAT1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-629622
startCoordinate	2

Referrals

(input)	[BlackBoxEvent:R-HSA-8983841] STAT1 associates with IL6ST:IL6ST [BlackBoxEvent:R-HSA-8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor [BlackBoxEvent:R-HSA-8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor [BlackBoxEvent:R-HSA-8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex [Reaction:R-HSA-9008015] RUNX2 binds STAT1
(hasComponent)	[Complex:R-HSA-8983842] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] [Complex:R-HSA-8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [Complex:R-HSA-8983998] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] [Complex:R-HSA-8950267] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] [Complex:R-HSA-9008005] RUNX2:STAT1 [cytosol]
(hasMember)	[DefinedSet:R-HSA-6790032] STAT3-upregulated cytosolic proteins [cytosol] [DefinedSet:R-HSA-6788573] STAT1,STAT3,STAT6 [cytosol] [DefinedSet:R-HSA-9009216] STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] [DefinedSet:R-HSA-9010176] STAT1, STAT3, STAT5 [cytosol] [DefinedSet:R-HSA-9006868] STAT1,STAT3,STAT4,STAT5 [cytosol] [CandidateSet:R-HSA-1169379] ISG15 targets [cytosol] [DefinedSet:R-HSA-1112559] STAT1, STAT3 [cytosol] [DefinedSet:R-HSA-380756] STAT family members [cytosol] [DefinedSet:R-HSA-1433551] STATs [cytosol] [DefinedSet:R-HSA-9729448] STAT1,STAT2 [cytosol]
(activeUnit)	[NegativeRegulation:R-HSA-9008011] Negative regulation by 'RUNX2:STAT1 [cytosol]'

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