Reactome | STAT1 [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] - Canis familiaris [Complex:R-CFA-8983842] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] - Canis familiaris [Complex:R-CFA-8983998] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] - Canis familiaris
consumedByEvent	[BlackBoxEvent:R-CFA-8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor - Canis familiaris [BlackBoxEvent:R-CFA-9865511] Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE - Canis familiaris [BlackBoxEvent:R-CFA-8983841] STAT1 associates with IL6ST:IL6ST - Canis familiaris [BlackBoxEvent:R-CFA-8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex - Canis familiaris [BlackBoxEvent:R-CFA-8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10252150
displayName	STAT1 [cytosol]
endCoordinate	750
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-629622] STAT1 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-CFA-6788573] STAT1,STAT3,STAT6 [cytosol] - Canis familiaris [DefinedSet:R-CFA-1112559] STAT1, STAT3 [cytosol] - Canis familiaris [DefinedSet:R-CFA-380756] STAT family members [cytosol] - Canis familiaris [CandidateSet:R-CFA-1169379] ISG15 targets [cytosol] - Canis familiaris
name	STAT1 STAT1 A0A8I3PSA1
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3PSA1] UniProt:A0A8I3PSA1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-629622
startCoordinate	2

(input)	[BlackBoxEvent:R-CFA-8983841] STAT1 associates with IL6ST:IL6ST [BlackBoxEvent:R-CFA-8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor [BlackBoxEvent:R-CFA-8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor [BlackBoxEvent:R-CFA-8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex [BlackBoxEvent:R-CFA-9865511] Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE
(hasComponent)	[Complex:R-CFA-8983842] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] [Complex:R-CFA-8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [Complex:R-CFA-8983998] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] [Complex:R-CFA-8950267] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane]
(hasMember)	[DefinedSet:R-CFA-6788573] STAT1,STAT3,STAT6 [cytosol] [DefinedSet:R-CFA-380756] STAT family members [cytosol] [DefinedSet:R-CFA-9006868] STAT1,STAT3,STAT4,STAT5 [cytosol] [DefinedSet:R-CFA-9009216] STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] [DefinedSet:R-CFA-1433551] STATs [cytosol] [CandidateSet:R-CFA-1169379] ISG15 targets [cytosol] [DefinedSet:R-CFA-1112559] STAT1, STAT3 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-629622] STAT1 [cytosol]

STAT1 [cytosol] Show undefined attributes

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