Reactome | FOXO4 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

FOXO4 [nucleoplasm] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-9620827] FOXO1,FOXO3,(FOXO4) [nucleoplasm] - Homo sapiens [CandidateSet:R-HSA-9618003] FOXO3,(FOXO1,FOXO4) [nucleoplasm] - Homo sapiens
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9735435] FOXO4:MEF2C:NKX2-5:MYOCD gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9735442] FOXO4, MEF2C, and NKX2-5 bind the MYOCD gene - Homo sapiens [Reaction:R-HSA-9617927] FOXO4 binds ATXN3 - Homo sapiens [Reaction:R-HSA-9617660] ROS oxidize FOXO4 cysteine residues - Homo sapiens
created	[InstanceEdit:5690100] Jupe, Steve, 2015-04-27
dbId	5690183
displayName	FOXO4 [nucleoplasm]
endCoordinate	505
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9617671] Foxo4 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5690183] Foxo4 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-5690183] FOXO4 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-5690183] FOXO4 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-5690183] FOXO4 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-5690183] foxo4 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-5690183] foxo4 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-5690183] FOXO4 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-5690183] foxo [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-5690183] daf-16 [nucleoplasm] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-5689977] TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] - Homo sapiens [CandidateSet:R-HSA-199272] FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] - Homo sapiens [DefinedSet:R-HSA-9623256] FOXO1,FOXO1:PPARGC1A,FOXO3,FOXO4,FOXO6 [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:8871616] Weiser, JD
name	FOXO4 Forkhead box protein O4 FOXO4_HUMAN
positivelyRegulates	[PositiveRegulation:9614696] Positive regulation by 'FOXO4 [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-9617735] TXN disrupts FOXO4 complex with EP300 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P98177] UniProt:P98177 FOXO4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5690183
startCoordinate	1

Referrals

(hasMember)	[DefinedSet:R-HSA-5689977] TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] [DefinedSet:R-HSA-9623398] FOXO1:PPARGC1A,FOXO3,FOXO4 [nucleoplasm] [DefinedSet:R-HSA-9623256] FOXO1,FOXO1:PPARGC1A,FOXO3,FOXO4,FOXO6 [nucleoplasm] [CandidateSet:R-HSA-9617860] FOXO3,FOXO4,(FOXO1) [nucleoplasm] [DefinedSet:R-HSA-9623421] FOXO3,FOXO4 [nucleoplasm] [CandidateSet:R-HSA-199272] FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] [DefinedSet:R-HSA-9617987] FOXO1,FOXO3,FOXO4 [nucleoplasm]
(hasComponent)	[Complex:R-HSA-9735435] FOXO4:MEF2C:NKX2-5:MYOCD gene [nucleoplasm] [Complex:R-HSA-9617923] FOXO4:ATXN3 [nucleoplasm]
(input)	[Reaction:R-HSA-9735442] FOXO4, MEF2C, and NKX2-5 bind the MYOCD gene [Reaction:R-HSA-9617660] ROS oxidize FOXO4 cysteine residues [Reaction:R-HSA-9617927] FOXO4 binds ATXN3
(output)	[Reaction:R-HSA-9617735] TXN disrupts FOXO4 complex with EP300
(regulator)	[PositiveRegulation:9614696] Positive regulation by 'FOXO4 [nucleoplasm]'
(hasCandidate)	[CandidateSet:R-HSA-9620827] FOXO1,FOXO3,(FOXO4) [nucleoplasm] [CandidateSet:R-HSA-9618003] FOXO3,(FOXO1,FOXO4) [nucleoplasm]

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