Reactome | Foxo4 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-MMU-9618003] FOXO3,(FOXO1,FOXO4) [nucleoplasm] - Mus musculus
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-9735440] Foxo4:Mef2c:Nkx2-5:Myocd gene [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9735428] Foxo4, Mef2c, and Nkx2-5 bind the Myocd gene - Mus musculus [Reaction:R-MMU-9617927] FOXO4 binds ATXN3 - Mus musculus [Reaction:R-NUL-9617903] Foxo4 binds GADD45A gene promoter - Homo sapiens [Reaction:R-MMU-9617657] ROS oxidize Foxo4 cysteine residues - Mus musculus
created	[InstanceEdit:9617670] Orlic-Milacic, Marija, 2018-08-30
dbId	9617671
displayName	Foxo4 [nucleoplasm]
endCoordinate	505
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5690183] FOXO4 [nucleoplasm] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-MMU-5689977] TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] - Mus musculus [CandidateSet:R-MMU-199272] FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] - Mus musculus
name	Foxo4 Forkhead box protein O4 FOXO4_MOUSE
producedByEvent	[Reaction:R-NUL-9617742] TXN disrupts Foxo4 comples with EP300 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q9WVH3] UniProt:Q9WVH3 Foxo4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-9617671
startCoordinate	1

(hasMember)	[DefinedSet:R-MMU-5689977] TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] [CandidateSet:R-MMU-9617860] FOXO3,FOXO4,(FOXO1) [nucleoplasm] [DefinedSet:R-MMU-9623421] FOXO3,FOXO4 [nucleoplasm] [CandidateSet:R-MMU-199272] FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] [DefinedSet:R-MMU-9617987] FOXO1,FOXO3,FOXO4 [nucleoplasm]
(hasComponent)	[Complex:R-MMU-9735440] Foxo4:Mef2c:Nkx2-5:Myocd gene [nucleoplasm] [Complex:R-MMU-9617923] FOXO4:ATXN3 [nucleoplasm] [Complex:R-NUL-9617900] Foxo4:GADD45A gene [nucleoplasm]
(input)	[Reaction:R-MMU-9735428] Foxo4, Mef2c, and Nkx2-5 bind the Myocd gene [Reaction:R-MMU-9617657] ROS oxidize Foxo4 cysteine residues [Reaction:R-MMU-9617927] FOXO4 binds ATXN3 [Reaction:R-NUL-9617903] Foxo4 binds GADD45A gene promoter
(output)	[Reaction:R-NUL-9617742] TXN disrupts Foxo4 comples with EP300
(activeUnit)	[PositiveGeneExpressionRegulation:9617913] Positive gene expression regulation by 'Foxo4:GADD45A gene [nucleoplasm]'
(hasCandidate)	[CandidateSet:R-MMU-9618003] FOXO3,(FOXO1,FOXO4) [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5690183] FOXO4 [nucleoplasm]