Reactome | ROS oxidize FOXO4 cysteine residues

Schema > Reaction > Entries

authored	[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018-10-11
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9617664] Orlic-Milacic, Marija, 2018-08-30
dbId	9617660
displayName	ROS oxidize FOXO4 cysteine residues
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
eventOf	[Pathway:R-HSA-9617629] Regulation of FOXO transcriptional activity by acetylation - Homo sapiens
followingEvent	[Reaction:R-HSA-9617683] EP300,CREBBP bind SOH-C481-FOXO4 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9617657] ROS oxidize Foxo4 cysteine residues - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-5690183] FOXO4 [nucleoplasm] [SimpleEntity:R-ALL-3785707] ROS [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ROS oxidize FOXO4 cysteine residues
output	[EntityWithAccessionedSequence:R-HSA-9617655] SOH-C481-FOXO4 [nucleoplasm]
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9625979] Donlon, Timothy, 2018-10-17 [InstanceEdit:9626974] Bertaggia, Enrico, 2018-10-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9617660
summation	[Summation:9617665] Reactive oxygen species (ROS) oxidize cysteine residue(s) of...

(hasEvent)	[Pathway:R-HSA-9617629] Regulation of FOXO transcriptional activity by acetylation
(precedingEvent)	[Reaction:R-HSA-9617683] EP300,CREBBP bind SOH-C481-FOXO4
(inferredTo)	[Reaction:R-MMU-9617657] ROS oxidize Foxo4 cysteine residues

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