Reactome | DDIT4 binds 14-3-3 dimer

Schema > Reaction > Entries

DDIT4 binds 14-3-3 dimer Show undefined attributes

authored	[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5632737] Orlic-Milacic, Marija, 2014-10-28
dbId	5632738
displayName	DDIT4 binds 14-3-3 dimer
edited	[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
eventOf	[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes - Homo sapiens
input	[DefinedSet:R-HSA-1445138] 14-3-3 dimer [cytosol] [EntityWithAccessionedSequence:R-HSA-5632374] DDIT4 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5632740] Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling [LiteratureReference:5632356] p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	DDIT4 binds 14-3-3 dimer
orthologousEvent	[Reaction:R-DRE-5632738] DDIT4 binds 14-3-3 dimer - Danio rerio [Reaction:R-DME-5632738] DDIT4 binds 14-3-3 dimer - Drosophila melanogaster [Reaction:R-GGA-5632738] DDIT4 binds 14-3-3 dimer - Gallus gallus [Reaction:R-XTR-5632738] DDIT4 binds 14-3-3 dimer - Xenopus tropicalis [Reaction:R-SSC-5632738] DDIT4 binds 14-3-3 dimer - Sus scrofa [Reaction:R-BTA-5632738] DDIT4 binds 14-3-3 dimer - Bos taurus [Reaction:R-CFA-5632738] DDIT4 binds 14-3-3 dimer - Canis familiaris [Reaction:R-RNO-5632738] DDIT4 binds 14-3-3 dimer - Rattus norvegicus [Reaction:R-MMU-5632738] DDIT4 binds 14-3-3 dimer - Mus musculus
output	[Complex:R-HSA-5632741] DDIT4:14-3-3 dimer [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-5632386] TP63/TP53 stimulates transcription of DDIT4 gene - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5662800] Hwang, Paul M, 2014-12-30 [InstanceEdit:5662803] Kang, Ju-Gyeong, 2014-12-30 [InstanceEdit:5662801] Wang, Ping-yuan, 2014-12-30 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04 [InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5632738
summation	[Summation:5632744] DDIT4 (REDD1) binds 14-3-3 proteins through a conserved 14-3...

Referrals

(hasEvent)

[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes