Reactome | TP63/TP53 stimulates transcription of DDIT4 gene

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TP63/TP53 stimulates transcription of DDIT4 gene Show undefined attributes

authored	[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:5632395] Orlic-Milacic, Marija, 2014-10-28
dbId	5632386
displayName	TP63/TP53 stimulates transcription of DDIT4 gene
edited	[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
eventOf	[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes - Homo sapiens
followingEvent	[Reaction:R-HSA-5632738] DDIT4 binds 14-3-3 dimer - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5632378] DDIT4 Gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5632390] REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP63/TP53 stimulates transcription of DDIT4 gene
output	[EntityWithAccessionedSequence:R-HSA-5632374] DDIT4 [cytosol]
precedingEvent	[Reaction:R-HSA-5632393] TP63/TP53 bind the DDIT4 gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-5632389] Positive gene expression regulation by 'TP63/T53:DDIT4 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642089] Positive gene expression regulation by 'TP63/T53:DDIT4 Gene [nucleoplasm]' REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5662800] Hwang, Paul M, 2014-12-30 [InstanceEdit:5662803] Kang, Ju-Gyeong, 2014-12-30 [InstanceEdit:5662801] Wang, Ping-yuan, 2014-12-30 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04 [InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5632386
summation	[Summation:5632705] Transcription of DDIT4 (REDD1) gene is stimulated by TP63, b...
updateTrackers	[UpdateTracker:9783559] Update Tracker - [BlackBoxEvent:5632386] TP63/TP53 stimulates transcription of DDIT4 gene - v56:[modifyText, removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9783559] Update Tracker - [BlackBoxEvent:5632386] TP63/TP53 stimulates transcription of DDIT4 gene - v56:[modifyText, removeLiteratureReference]
(hasEvent)	[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes
(precedingEvent)	[Reaction:R-HSA-5632738] DDIT4 binds 14-3-3 dimer

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