Reactome | ASAP1 stimulates GTPase activity of ARF4

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ASAP1 stimulates GTPase activity of ARF4 Show undefined attributes

authored	[InstanceEdit:5620934] Rothfels, Karen, 2014-08-27
catalystActivity	[CatalystActivity:5623515] GTPase activity of RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:5623514] Rothfels, Karen, 2014-09-12
dbId	5623513
displayName	ASAP1 stimulates GTPase activity of ARF4
edited	[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
eventOf	[Pathway:R-HSA-5620916] VxPx cargo-targeting to cilium - Homo sapiens
followingEvent	[Reaction:R-HSA-5623519] RAB3IP and RAB8A bind to the ciliary targeting complex - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-HSA-5623434] RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5623294] Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4 [LiteratureReference:5623289] Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome [LiteratureReference:5623300] Crosstalk of Arf and Rab GTPases en route to cilia
modified	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
name	ASAP1 stimulates GTPase activity of ARF4
orthologousEvent	[Reaction:R-DME-5623513] ASAP1 stimulates GTPase activity of ARF4 - Drosophila melanogaster [Reaction:R-GGA-5623513] ASAP1 stimulates GTPase activity of ARF4 - Gallus gallus [Reaction:R-DRE-5623513] ASAP1 stimulates GTPase activity of ARF4 - Danio rerio [Reaction:R-SSC-5623513] ASAP1 stimulates GTPase activity of ARF4 - Sus scrofa [Reaction:R-BTA-5623513] ASAP1 stimulates GTPase activity of ARF4 - Bos taurus [Reaction:R-CFA-5623513] ASAP1 stimulates GTPase activity of ARF4 - Canis familiaris [Reaction:R-RNO-5623513] ASAP1 stimulates GTPase activity of ARF4 - Rattus norvegicus [Reaction:R-MMU-5623513] ASAP1 stimulates GTPase activity of ARF4 - Mus musculus
output	[Complex:R-HSA-5623424] ARF4:GDP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-HSA-5623437] RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane]
precedingEvent	[Reaction:R-HSA-5620921] ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex - Homo sapiens
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10 [InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5623513
summation	[Summation:5623360] Recruitment of RAB11FIP3 to the trans-Golgi network (TGN) si...

Referrals

(hasEvent)	[Pathway:R-HSA-5620916] VxPx cargo-targeting to cilium
(precedingEvent)	[Reaction:R-HSA-5623519] RAB3IP and RAB8A bind to the ciliary targeting complex