Reactome | ASAP1 stimulates GTPase activity of ARF4

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ASAP1 stimulates GTPase activity of ARF4 Show undefined attributes

catalystActivity	[CatalystActivity:10620341] GTPase activity of RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10620343
displayName	ASAP1 stimulates GTPase activity of ARF4
eventOf	[Pathway:R-GGA-5620916] VxPx cargo-targeting to cilium - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-5623519] RAB3IP and RAB8A bind to the ciliary targeting complex - Gallus gallus
inferredFrom	[Reaction:R-HSA-5623513] ASAP1 stimulates GTPase activity of ARF4 - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-GGA-5623434] RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane]
isInDisease	false
isInferred	true
name	ASAP1 stimulates GTPase activity of ARF4
output	[Complex:R-GGA-5623424] ARF4:GDP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-GGA-5623437] RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane]
precedingEvent	[Reaction:R-GGA-5620921] ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex - Gallus gallus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5623513
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5620916] VxPx cargo-targeting to cilium
(precedingEvent)	[Reaction:R-GGA-5623519] RAB3IP and RAB8A bind to the ciliary targeting complex
(inferredTo)	[Reaction:R-HSA-5623513] ASAP1 stimulates GTPase activity of ARF4